ArticleJournal of clinical hypertension (Greenwich, Conn.)2023
Association between salt sensitivity of blood pressure and the risk of hypertension in a Chinese Tibetan population.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 9 citations in OpenAlex.
- Abnormal circadian pattern of urinary sodium excretion and chronic kidney disease progression.BMC nephrology · 2026Article
- Study on the ambulatory blood pressure phenotype and its correlation with hemoglobin concentration in untreated hypertensive individuals permanently living in plateau areas.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Dental Caries and Associated Factors in Tibetan School-Age Children in Gannan, China.International dental journal · 2025Article
- The association between urine-estimated salt intake and hypertension: findings of a population-based study.Clinical hypertension · 2025Article
- Risk factors and a predictive model for left ventricular hypertrophy in young adults with salt-sensitive hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Association between salt sensitivity of blood pressure and the risk of hypertension in a Chinese Tibetan population.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
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13 authors at 3 institutions in 1 country.
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Abstract
Epidemiological studies have confirmed salt sensitivity as a crucial risk factor for the development of hypertension. However, few studies have investigated the association between salt sensitivity of blood pressure (SSBP) and hypertension in Chinese Tibetan population. Therefore, we conducted a cross-sectional study based on a Tibetan population to evaluate the association between SSBP and the risk of hypertension. Seven hundred and eighty-four participants with hypertension and 645 participants without hypertension were included from five villages in Tibetan Autonomous Region of Gannan during 2013-2014. The assessment of salt sensitivity (SS) and non-salt sensitivity (NSS) was performed according to mean arterial pressure (MAP) changes by the modified Sullivan's acute oral saline load and diuresis shrinkage test (MSAOSL-DST). Logistic regression models and restricted cubic models were used to examine the association between SSBP and hypertension. There were 554 (70.5%) salt-sensitive participants with hypertension and 412 (63.9%) salt-sensitive participants without hypertension in this study. Compared with individuals with NSS, individuals with SS had a significantly increased risk of hypertension, and the multiple-adjusted odds ratios were 2.582 with 95% confidence interval of 1.357-4.912. Furthermore, a significant linear trend was found between MAP changes and hypertension. Subgroup analyses showed significant and stronger associations between SSBP and the risk of hypertension in the older (age ≥ 55 years old), males and participants who took exercise less than 1 time per week. Our results suggest that SS is associated with an increased risk of hypertension in Tibetan population, indicating a need for clinicians dealing with SSBP to decrease the risk of hypertension.
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