Evidence map›Paper›PMID 37120582›Full record

ArticleNature communications2023

PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysis.

Nicole L Bertschi, Oliver Steck, Fabian Luther, Cecilia Bazzini, Leonhard von Meyenn, Stefanie Schärli, Angela Vallone, Andrea Felser, Irene Keller, Olivier Friedli and 10 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Nicole L Bertschi *Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-4664-1634
Oliver Steck *Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Fabian Luther *Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Cecilia BazziniDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Leonhard von MeyennDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0003-2490-1412
Stefanie SchärliDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0001-9125-9445
Angela ValloneDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Andrea FelserInstitute of Clinical Chemistry, University of Bern, Bern, Switzerland.
Irene KellerInterfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
Olivier FriedliInstitute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland.ORCID 0000-0001-7708-3025
Stefan FreigangInstitute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland.ORCID 0000-0003-4438-7828
Nadja BegréDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Susanne Radonjic-HoesliDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-5742-0765
Cristina LamosDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Max Philip GabuttiDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Michael BenzaquenDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-3584-0304
Markus LaimerDepartment of Diabetes, Endocrinology, Nutritional Medicine and Metabolism (UDEM), Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-7622-0822
Dagmar SimonDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Jean-Marc NuofferInstitute of Clinical Chemistry, University of Bern, Bern, Switzerland.ORCID 0000-0003-3650-6153
Christoph SchlapbachDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. christoph.schlapbach@insel.ch.ORCID 0000-0003-0258-1243
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T helper 9 (T

Indexed as

Interleukin-9PPAR gammaGlucoseGlycolysisHumansInflammationInterleukin-13T-Lymphocytes, Helper-InducerGlucoseInterleukin-13Interleukin-9PPAR gammaPPARG protein, human

Identifiers

PMID37120582
PMCPMC10148883
OpenAlexW4367368645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.