Evidence map›Paper›PMID 37120406›Full record

Observational studyAnais brasileiros de dermatologia

Epidemiological characteristics of leprosy from 2000 to 2019 in a state with low endemicity in southern Brazil.

Paulo Cezar de Moraes, Letícia Maria Eidt, Alessandra Koehler, Leonardo Girardi Ransan, Maria Lúcia Scrofeneker

Abstract readObservational Study
In one paragraph

Observational study in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paulo Cezar de MoraesDepartment of Sanitary Dermatology, Sanitary Dermatology Outpatient Clinic, State Health Secretariat of Rio Grande do Sul, Porto Alegre, RS, Brazil; Postgraduation Program in Medicine ‒ Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Letícia Maria EidtDepartment of Sanitary Dermatology, Sanitary Dermatology Outpatient Clinic, State Health Secretariat of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Alessandra KoehlerDepartment of Microbiology, Immunology and Parasitology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Postgraduation Program in Medicine ‒ Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Leonardo Girardi RansanDepartment of Microbiology, Immunology and Parasitology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Postgraduation Program in Medicine ‒ Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Maria Lúcia ScrofenekerDepartment of Microbiology, Immunology and Parasitology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Postgraduation Program in Medicine ‒ Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address: scrofern@ufrgs.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeprosy is an infectious and contagious disease caused by Mycobacterium leprae and is mainly characterized by lesions in the skin and peripheral nerves. In Brazil, it is a public health problem due to its high endemicity. However, the state of Rio Grande do Sul presents low endemicity of this disease.

objectiveTo characterize the epidemiological profile of leprosy in the state of Rio Grande do Sul from 2000 to 2019.

methodsThis was a retrospective observational study. Epidemiological data were collected from the Notifiable Diseases Information System (SINAN, Sistema de Informação de Agravos de Notificação).

resultsAmong the 497 municipalities in the state, 357 (71.8%) registered cases of leprosy in the assessed period, with an average of 212 (81.5%) new cases per year. The average detection rate was 1.61 new cases per 100,000 inhabitants. The male sex was predominant (51.9%) and the mean age was 50.4 years. Regarding the epidemiological clinical profile; 79.0% of the patients were multibacillary; 37.5% presented the borderline clinical form; 16% had grade 2 physical disability at diagnosis and bacilloscopy was positive in 35.4% of cases. As for treatment, 73.8% of the cases were treated with the standard multibacillary therapeutic regimen. STUDY LIMITATIONS: There were missing/inconsistent data in the database available.

conclusionsThe findings observed in this study indicate that the state presents a low endemicity profile of the disease and these results can support adequate health policies relevant to the reality of Rio Grande do Sul, inserted in a national scenario of highly endemic leprosy.

Indexed as

LeprosyPersons with DisabilitiesBrazilHumansMaleMiddle AgedMycobacterium lepraeRetrospective StudiesEpidemiologyHealth profileLeprosyPrevalence

Identifiers

PMID37120406
PMCPMC10404493

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.