Evidence map›Paper›PMID 37119964›Full record

ReviewDrug discovery today2023

SNAP@CQD as a promising therapeutic vehicle against HCoVs: An overview.

Satyaki Chatterjee, Arnab Chakraborty, Jyotiparna Banik, Sanya Mahindru, Arun K Sharma, Monalisa Mukherjee

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Drug discovery today, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Satyaki ChatterjeeAmity Institute of Click Chemistry Research and Studies (AICCRS), Amity University, Noida, UP 201301, India.
Arnab ChakrabortyAmity Institute of Click Chemistry Research and Studies (AICCRS), Amity University, Noida, UP 201301, India.
Jyotiparna BanikDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, ON M5S 3E5, Canada.
Sanya MahindruAmity Institute of Biotechnology, Amity University, Noida 201303, India.
Arun K SharmaDepartment of Pharmacology, Amity Institute of Pharmacy, Amity University, Gurugram, Haryana 122413, India.
Monalisa MukherjeeAmity Institute of Click Chemistry Research and Studies (AICCRS), Amity University, Noida, UP 201301, India; Amity Institute of Biotechnology, Amity University, Noida 201303, India. Electronic address: mmukherjee@amity.edu.
Amity University · INUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report discusses potential therapies for treating human coronaviruses (HCoVs) and their economic impact. Specifically, we explore therapeutics that can support the body's immune response, including immunoglobulin (Ig)A, IgG and T-cell responses, to inhibit the viral replication cycle and improve respiratory function. We hypothesize that carbon quantum dots conjugated with S-nitroso-N-acetylpenicillamine (SNAP) could be a synergistic alternative cure for treating respiratory injuries caused by HCoV infections. To achieve this, we propose developing aerosol sprays containing SNAP moieties that release nitric oxide and are conjugated onto promising nanostructured materials. These sprays could combat HCoVs by inhibiting viral replication and improving respiratory function. Furthermore, they could potentially provide other benefits, such as providing novel possibilities for nasal vaccines in the future.

Indexed as

Nitric OxideVirus ReplicationHumansS-Nitroso-N-AcetylpenicillamineNitric OxideS-Nitroso-N-Acetylpenicillamineaerosol spraycarbon quantum dotsNO radicalSARS-CoV-2SNAP

Identifiers

PMID37119964
PMCPMC10140467
OpenAlexW4367315876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.