Evidence map›Paper›PMID 37119497›Full record

ArticleProbiotics and antimicrobial proteins2024

Safety Evaluation of a Novel Potentially Probiotic Limosilactobacillus fermentum in Rats.

José Patrocínio Ribeiro Cruz Neto, Alison Macário de Oliveira, Kataryne Árabe Rimá de Oliveira, Karoliny Brito Sampaio, Maria Letícia da Veiga Dutra, Micaelle Oliveira de Luna Freire, Evandro Leite de Souza, José Luiz de Brito Alves

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Safety and immunostimulatory potential evaluation of Limosilactobacillus fermentum isolated from millet-based fermented food in mice.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. A Mix of Potentially ProbioticMicroorganisms · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

José Patrocínio Ribeiro Cruz NetoDepartment of Nutrition, Health Sciences Center, Federal University of Paraíba, Campus I - Jd. Cidade Universitária, 58051-900, João Pessoa, PB, Brazil.
Alison Macário de OliveiraDepartment of Biochemistry, Biological Sciences Center, Federal University of Pernambuco, Recife, PE, Brazil.
Kataryne Árabe Rimá de OliveiraDepartment of Nutrition, Health Sciences Center, Federal University of Paraíba, Campus I - Jd. Cidade Universitária, 58051-900, João Pessoa, PB, Brazil.
Karoliny Brito SampaioDepartment of Nutrition, Health Sciences Center, Federal University of Paraíba, Campus I - Jd. Cidade Universitária, 58051-900, João Pessoa, PB, Brazil.
Maria Letícia da Veiga DutraDepartment of Nutrition, Health Sciences Center, Federal University of Paraíba, Campus I - Jd. Cidade Universitária, 58051-900, João Pessoa, PB, Brazil.
Micaelle Oliveira de Luna FreireDepartment of Nutrition, Health Sciences Center, Federal University of Paraíba, Campus I - Jd. Cidade Universitária, 58051-900, João Pessoa, PB, Brazil.
Evandro Leite de SouzaDepartment of Nutrition, Health Sciences Center, Federal University of Paraíba, Campus I - Jd. Cidade Universitária, 58051-900, João Pessoa, PB, Brazil.
José Luiz de Brito AlvesDepartment of Nutrition, Health Sciences Center, Federal University of Paraíba, Campus I - Jd. Cidade Universitária, 58051-900, João Pessoa, PB, Brazil. jose.luiz@academico.ufpb.br.
Universidade Federal da Paraíba · BRUniversidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limosilactobacillus (L) fermentum (strains 139, 263, 296) is a novel probiotic mixture isolated from fruit processing by-products. The use of this formulation has been associated with improvements in cardiometabolic, inflammatory, and oxidative stress parameters. The present study evaluated the safety of a potential multi-strain probiotic by genotoxicity (micronucleus assay) and subchronic toxicity study (13-week repeated dose). In the genotoxicity evaluation, L. fermentum 139, 263, 296 did not increase the frequency of micronuclei in erythrocytes of rats of both sexes at doses up to 10

Indexed as

Limosilactobacillus fermentumProbioticsAnimalsFemaleMaleMicronucleus TestsRatsRats, WistarGenotoxicityLimosilactobacillus fermentumProbioticsSafetySubchronic general toxicity

Identifiers

PMID37119497
OpenAlexW4367367916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.