ArticleUpdates in surgery2023
The efficacy of hemoglobin, albumin, lymphocytes, and platelets (HALP) score in signifying acute appendicitis severity and postoperative outcomes.
Article in Updates in surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 16 citations in OpenAlex.
- The utility of HALP, M-HALP, and the newly developed CANP scores in predicting prognosis of acute appendicitis.Updates in surgery · 2026Article
- The role of the HALP score and inflammatory biomarkers in differentiating complicated and uncomplicated acute appendicitis: a retrospective cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Prognostic Value of HALP and PNI Scores in Predicting 6-Month Mortality Among Geriatric Hip Fracture Patients.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- An Evaluation of the Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) Score in Cushing's Syndrome and Mild Autonomous Cortisol Secretion.Journal of clinical medicine · 2025Article
- Prognostic role of HALP score, CRP/albumin ratio and CALLY index in diabetic foot ulcer-related major amputations.Langenbeck's archives of surgery · 2025Article
- Assessing hemoglobin, albumin, lymphocyte, platelet (HALP) score in predicting strangulation and resection in hernia surgery.European journal of medical research · 2025Article
- Comparative evaluation of the diagnostic value of HALP Score and systemic inflammatory immune index biomarkers in childhood appendicitis.Pakistan journal of medical sciences · 2025Article
- Predictive Value of the Cally Score in Determining Surgical Strategy for Complicated Left-Sided Colonic Diverticulitis: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2025Article
- The L-shaped relationship between HALP score and one-year mortality in critically ill surgical patients: a retrospective cohort study.Scientific reports · 2025Article
- Predictive value of the HALP score in differentiating complicated and uncomplicated acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Delta neutrophil index, CRP/albumin ratio, procalcitonin, immature granulocytes, and HALP score in acute appendicitis: Best performing biomarker?Open medicine (Warsaw, Poland) · 2025Article
- Article
- Evaluation of Hemoglobin, Albumin, Lymphocyte, and Platelet Score, Neutrophil-to-Lymphocyte Ratio, and Platelet-to-Lymphocyte Ratio in Pediatric Patients with Rotavirus Enteritis.Journal of clinical practice and research · 2025Article
- Analysis of risk factors associated with the development and postoperative complications of complicated acute appendicitis in elderly patients.Frontiers in surgery · 2025Article
- A nomogram based on HALP score for predicting 28-day mortality in ICU-admitted cancer patients.Updates in surgery · 2024Article
- Comparison of the ability of newly inflammatory markers to predict complicated appendicitis.Open medicine (Warsaw, Poland) · 2024Article
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2 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The HALP score, which is a combined index composed of hemoglobin, albumin, lymphocyte, and platelet, is a new indicator showing both inflammation and nutritional status. This study aims to evaluate the relationship of this combined index consisting of simple laboratory values with the degree of appendicitis complication and postoperative results in patients operated on for acute appendicitis. The data of 684 patients operated for acute appendicitis between January 2017 and December 2022 and inclusion criteria were analyzed with a single-center retrospective cross-sectional study design. Using routine laboratory data, patients' HALP scores were divided into two groups as low and high. The cut-off value of the HALP score according to the presence of postoperative complications was determined as < 31.2 by ROC analysis and the ROC curve. Patients were grouped as HALP score cut-off value below (group 1) and above (group 2). Complicated appendicitis and postoperative outcomes were compared to the HALP score groups. According to the cut-off value of the HALP score, 113 (16.5%) of the patients were in Group 1, and 571 (83.5%) were in Group 2. Complications developed in 15 (26%) patients (p < 0.001). Low HALP scores were a significant risk factor for peri-appendicular abscess (OR 29.12 95% CI 12.39-68.43), appendicitis perforation (OR = 20.82 95% 12.67-34.19), gangrenous appendicitis (OR = 35, 54, 95% 13.33-94.77), and postoperative complications (OR = 15.29 95% 7.95-29.41) (p < 0.001). Besides clinical and radiological findings, the HALP score shows the degree of acute appendicitis complication. It can be used as a simple, inexpensive, and easily applicable diagnostic tool.
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