Evidence map›Paper›PMID 37119307›Full record

SynthesisGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Outcome measures in childhood glaucoma: a systematic review of randomized controlled trials.

Gurkaran S Sarohia, Maram E A Abdalla Elsayed, Carlos Eduardo Solarte, Stella J Hornby, John Brookes, Ta Chen Peter Chang, Rizwan Malik

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gurkaran S SarohiaDepartment of Ophthalmology and Visual Sciences, University of Alberta, 400, 10924, 107 Avenue, Edmonton, AB, T5H 0X5, Canada.
Maram E A Abdalla ElsayedOxford Eye Hospital, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK.
Carlos Eduardo SolarteDepartment of Ophthalmology and Visual Sciences, University of Alberta, 400, 10924, 107 Avenue, Edmonton, AB, T5H 0X5, Canada. solarte@ualberta.ca.ORCID http://orcid.org/0000-0002-4763-5586
Stella J HornbyOxford Eye Hospital, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK.
John BrookesGlaucoma Department, Moorfields Eye Hospital, London, UK.
Ta Chen Peter ChangBascom Palmer Eye Institute, Miami, FL, USA.
Rizwan MalikDepartment of Surgery, Sheikh Khalifa Medical City, Abu Dhabi, UAE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo synthesize the outcome measures used by randomized controlled trials (RCTs) for childhood glaucoma.

methodsMEDLINE, EMBASE, and Scopus were searched from inception to February 17, 2023. Randomized controlled trials and observational studies related to childhood glaucoma were included. Primary and secondary outcomes were extracted and the data was used to generate a literature review.

resultsThis review identified 42 unique reports pertaining to childhood glaucomas. Most of the studies originated from Egypt, India, and the USA. Intraocular pressure (IOP) outcomes were the most frequent outcomes studied, followed by clinical outcomes and safety outcomes. Clinical outcomes were the most common secondary outcomes studied, followed by IOP outcomes and safety outcomes.

conclusionsThis systematic review found heterogenous outcomes with IOP outcomes as the most studied primary outcome. As the remaining outcomes were not consistently utilized, this review highlights the need for a consensus on studies of pediatric glaucoma.

Indexed as

GlaucomaChildHumansIndiaIntraocular PressureOutcome Assessment, Health CareRandomized Controlled Trials as TopicOutcomesPediatric glaucomaRandomized clinical trialsSystematic review

Identifiers

PMID37119307

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.