Evidence map›Paper›PMID 37119231›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2023

Possible Link between Serotonin and Interleukin 18 on Suicidality in Patients with Acute Coronary Syndrome.

Jae-Min Kim, Hee-Ju Kang, Ju-Wan Kim, Wonsuk Choi, Sung-Wan Kim, Jung-Chul Kim, Byung Jo Chun, Youngkeun Ahn, Myung Ho Jeong

Abstract read
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Exploring Clinical Subgroups of Participants with Major Depressive Disorder that may Benefit from Adjunctive Minocycline Treatment.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Article
  2. Use of Serum Biomarkers to Aid Antidepressant Selection in Depressive Patients.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jae-Min KimDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0001-7409-6306
Hee-Ju KangDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0002-4784-4820
Ju-Wan KimDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0002-9888-1090
Wonsuk ChoiDepartment of Internal Medicine, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.ORCID https://orcid.org/0000-0002-0523-0839
Sung-Wan KimDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0002-6739-2163
Jung-Chul KimDepartment of Surgery, Chonnam National University Medical School and Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0002-6774-1861
Byung Jo ChunDepartment of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0002-5240-4213
Youngkeun AhnDepartment of Cardiology, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0003-2022-9366
Myung Ho JeongDepartment of Cardiology, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0003-2424-810X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We investigated effects of serum serotonin and interleukin 18 levels on suicidal ideation (SI) at acute and chronic phases of acute coronary syndrome (ACS). Methods: Recent-onset 969 ACS patients were evaluated for serum serotonin and interleukin 18 levels; and SI by the "suicidal thoughts" item of the Montgomery-Åsberg Depression Rating Scale. After 1-year, 711 patients were re-evaluated for SI. Logistic regression models were used adjustment for potential covariates. Results: Associations between serum interleukin 18 and SI at both phases were significant only in the lower serotonin group. Conclusion: By evaluating serum serotonin and interleukin 18 levels, the clinical prediction of SI of ACS may be improved.

Indexed as

Acute coronary syndromeInterleukin 18longitudinal studySerotoninSuicidal ideation

Identifiers

PMID37119231
PMCPMC10157011

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.