Evidence map›Paper›PMID 37118906›Full record

ArticleJournal of veterinary internal medicine

Concurrent chronic lymphocytic leukemia and primary hyperparathyroidism in a mule.

Kile S Townsend, Philip J Johnson, Lindsay L Donnelly, Alison M LaCarrubba, James C Lattimer, Brett Havis, Nora L Springer, Dae Y Kim

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kile S TownsendDepartment of Veterinary Medicine and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.ORCID https://orcid.org/0000-0001-8418-7842
Philip J JohnsonDepartment of Veterinary Medicine and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.ORCID https://orcid.org/0000-0002-8180-7601
Lindsay L DonnellyDepartment of Veterinary Medicine and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.ORCID https://orcid.org/0000-0001-9116-7428
Alison M LaCarrubbaDepartment of Veterinary Medicine and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.
James C LattimerDepartment of Veterinary Medicine and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.
Brett HavisDepartment of Veterinary Medicine and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.
Nora L SpringerDepartment of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, Tennessee, USA.ORCID https://orcid.org/0000-0003-4543-7313
Dae Y KimDepartment of Veterinary Medicine and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.
Missouri College · USKnoxville College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 26-year-old mule gelding was evaluated for chronic weight loss and decreased appetite. The mule had been losing weight and intermittently hypophagic for approximately 7 months. Laboratory analysis of whole blood and plasma identified severe total hypercalcemia, marked hypophosphatemia, markedly increased parathyroid hormone concentration, and marked lymphocytosis. A sestimibi scan intended to identify parathyroid gland tissue was nondiagnostic. Results of flow cytometry and PCR for antigen receptor rearrangement (PARR) were consistent with a B cell lymphoproliferative disorder, likely chronic lymphocytic leukemia (CLL). Although not previously described concurrently, these conditions may sometimes arise together, complicating definition of the underlying mechanism for weight loss and hypercalcemia in aged equids.

Indexed as

Horse DiseasesHypercalcemiaHyperparathyroidism, PrimaryLeukemia, Lymphocytic, Chronic, B-CellLymphocytosisAnimalsEquidaeHorsesMaleendocrinopathyequinehypercalcemiaimmunohistochemistryneoplasia

Identifiers

PMID37118906
PMCPMC10229365
OpenAlexW4367368750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.