Evidence map›Paper›PMID 37118826›Full record

ArticleJournal of ovarian research2023

Lyophilized equine platelet-rich plasma (L-GF

Ahmed Sabry S Abdoon, Ahmed M E Al-Atrash, Seham S Soliman, Amro M El-Sanea, Amina A Gamal El Din, Hossam M Fahmy

Open access · goldAbstract read
In one paragraph

Article in Journal of ovarian research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ahmed Sabry S AbdoonDepartment of Animal Reproduction and Artificial Insemination, Veterinary Research Institute, National Research Centre, Dokki, Cairo, 12622, Egypt. as.abdoon@nrc.sci.eg.ORCID http://orcid.org/0000-0002-8430-9325
Ahmed M E Al-AtrashMedical and Radio Protection Administration, Nuclear Materials Authority, Cairo, Egypt.
Seham S SolimanDepartment of Animal Reproduction and Artificial Insemination, Veterinary Research Institute, National Research Centre, Dokki, Cairo, 12622, Egypt.
Amro M El-SaneaDepartment of Animal Reproduction and Artificial Insemination, Veterinary Research Institute, National Research Centre, Dokki, Cairo, 12622, Egypt.
Amina A Gamal El DinDepartment of Pathology, Medicine and Clinical Studies Research Institute, National Research Centre, Dokki, Cairo, 12622, Egypt.
Hossam M FahmyLaboratory and Transfusion Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
National Research Centre · EGAin Shams University · EGNuclear Materials Authority · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe antineoplastic agent Cyclophosphamide (CP) induces reproductive toxicity. New strategies for protecting ovarian tissue damage in women with chemotherapy-induced reproductive toxicity are essential. This study was designed to evaluate the possible protective effect of combined treatment with L-GF METHODOLOGY: Forty mature female rats were assigned into four groups: First group, control: rats were intraperitoneally injected (IP) with 200 µl sterile saline solution on days 1 and 10; Group 2 (CP): were IP injected with 75 mg/kg on days 1 and 10 to induce POI); Group 3 (CP + L-GF

resultsOn day 21 of the experiment, body weight, ovarian parameters (Ovarian weight, uterine weight, the number of ovarian follicles, and corpora lutea (CL) were determined, and histopathological changes, blood profile, as well as antioxidant activity assessment, were performed. CP significantly suppresses ovarian and uterine functions and increased MAD, NO levels, RBCs, hemoglobin, WBCs, and platelet count compared to the control group ( P < 0.05). While, in CP + L-GF

conclusionco-administration of L-GF

Indexed as

AntioxidantsOxidative StressAnimalsBody WeightCyclophosphamideFemaleHorsesRatsRats, WistarAntioxidantsCyclophosphamideAntioxidantsBlood profileOvaryRatReproductive toxicityUterus

Identifiers

PMID37118826
PMCPMC10141944
OpenAlexW4367317141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.