Evidence map›Paper›PMID 37118720›Full record

ArticleBMC surgery2023

A new method for predicting the microvascular invasion status of hepatocellular carcinoma through neural network analysis.

Jinli Zheng, Xiaozhen Wei, Ning Wang, Xingyu Pu, Jiayin Yang, Li Jiang

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jinli Zheng *Liver Transplant Center, Transplant Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.
Xiaozhen Wei *Department of Anesthesia & Operation Center, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Ning WangDepartment of Liver Surgery, General Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.
Xingyu PuDepartment of Liver Surgery, General Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.
Jiayin YangLiver Transplant Center, Transplant Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.
Li JiangDepartment of Liver Surgery, General Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China. jianglihuaxi@163.com.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo determine the relationship between microvascular invasion (MVI) and the clinical features of hepatocellular carcinoma (HCC) and provide a method to evaluate MVI status by neutral network analysis.

methodsThe patients were divided into two groups (MVI-positive group and MVI-negative group). Univariate analysis and multivariate logistic regression analysis were carried out to identify the independent risk factors for MVI positivity. Neural network analysis was used to analyze the different importance of the risk factors in MVI prediction.

resultsWe enrolled 1697 patients in this study. We found that the independent prognostic factors were age, NEU, multiple tumors, AFP level and tumor diameter. By neural network analysis, we proposed that the level of AFP was the most important risk factor for HCC in predicting MVI status (the AUC was 0.704). However, age was the most important risk factor for early-stage HCC with a single tumor (the AUC was 0.605).

conclusionThrough the neutral network analysis, we could conclude that the level of AFP is the most important risk factor for MVI-positive patients and the age is the most important risk factor for early-stage HCC with a single tumor.

Indexed as

Carcinoma, HepatocellularLiver Neoplasmsalpha-FetoproteinsHumansNeoplasm InvasivenessRetrospective Studiesalpha-FetoproteinsHepatocellular carcinomaMicrovascular invasionNeural network analysis

Identifiers

PMID37118720
PMCPMC10148386
OpenAlexW4367310793

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.