ArticleBMC cardiovascular disorders2023
Association between albumin corrected anion gap and 30-day all-cause mortality of critically ill patients with acute myocardial infarction: a retrospective analysis based on the MIMIC-IV database.
Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Association of preoperative albumin-corrected anion gap with 28-day mortality in cardiac surgery patients: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- LDAR outperforms other albumin-derived indices in predicting 28-day ICU mortality in critically ill myocardial infarction patients: a two-cohort study.Frontiers in medicine · 2026Article
- Association Between Albumin-Corrected Anion Gap and Mortality in ICU Patients With Acute Heart Failure: A MIMIC-IV Cohort Study.Cardiovascular therapeutics · 2026Article
- Construction of a Mortality Prediction Model for Cardiac Arrest Patients Using Lactate Clearance Rate and Albumin-Corrected Anion Gap.Emergency medicine international · 2026Article
- Associations Between Albumin-Corrected Anion Gap and Mortality in Heart Failure Patients with Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Machine Learning-Based Nomogram with Boruta and LASSO for 28-Day Mortality Prediction in Critical COPD Patients: Role of the Albumin-Corrected Anion Gap.International journal of chronic obstructive pulmonary disease · 2026Article
- Association between albumin-corrected anion gap and 60-day all-cause mortality in critically ill shock patients.European journal of medical research · 2025Article
- Contribution of albumin-corrected anion gap and associated biomarkers to the mortality of patients with congestive heart failure: a retrospective cohort study.BMC cardiovascular disorders · 2025Article
- Albumin-corrected anion gap and risk of mortality among US adults.Archives of public health = Archives belges de sante publique · 2025Article
- Association between albumin-corrected anion gap and delirium in acute pancreatitis: insights from the MIMIC-IV database.BMC gastroenterology · 2025Article
- Association Between Albumin Corrected Anion Gap and 28-Day All-Cause Mortality in Patients With Acute Respiratory Failure in ICU: A Retrospective Study Based on the MIMIC-IV Database.The clinical respiratory journal · 2025Article
- Development of a nomogram model to predict 30-day mortality in ICU cancer patients with acute pulmonary embolism.Scientific reports · 2025Article
- Association of elevated albumin-corrected anion gap with all-cause mortality risk in atrial fibrillation: a retrospective study.BMC cardiovascular disorders · 2025Article
- Prognostic significance of albumin corrected anion gap in patients with acute pancreatitis: a novel perspective.Scientific reports · 2025Article
- Observational
- Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study.Frontiers in aging · 2025Article
- Relationship between albumin-corrected anion gap and non-alcoholic fatty liver disease: a cross-sectional analysis of NHANES 2017-2018.Frontiers in medicine · 2025Article
- Article
- Article
- The relationship between albumin-corrected anion gap and hyperuricemia and its role in cardiovascular risk assessment: mediation effect analysis of triglycerides and non-high-density lipoproteins.Frontiers in endocrinology · 2025Article
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6 authors.
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Abstract
backgroundThe anion gap (AG) has been linked to the prognosis of many cardiovascular disorders. However, the correlation between albumin-corrected anion gap (ACAG) and 30 d all-cause mortality of intensive care patients with acute myocardial infarction (AMI) is unclear. Furthermore, owing to the lack of studies, it is also unknown whether ACAG is more accurate than AG in predicting the mortality of AMI.
methodsThe Medical Information Mart for Intensive Care IV (MIMIC IV) dataset was used to provide patient data in this retrospective cohort study. ACAG is computed using the formulae: [4.4-{albumin (g/dl)}] × 2.5 + AG. The primary outcome was 30 d all-cause mortality intensive care patients with AMI. To explore the prognostic worthiness of ACAG, the receiver operating characteristic curve, smooth curve fitting, Cox regression model, and Kaplan survival analysis was performed.
resultsWe enrolled 2,160 patients in this study. ACAG had a better predictive value for 30 d all-cause mortality than AG, with an area under the curve of 0.66. The association between ACAG levels and overall mortality was nonlinear. In our model, after correcting for confounding factors, the ACAG was the independent predictor for 30 d all-cause mortality (HR 1.75, 95%CI 1.24, 2.47). ACAG K-M estimator curve analyses revealed that the group with ACAG ≥ 21.75 mmol/l had poor survival rate than the other group.
conclusionsHigh serum ACAG levels were a significant risk factor for 30 d all-cause mortality in critically ill patients with AMI. ACAG concentration and 30 d all-cause mortality had a nonlinear relationship. ACAG had better predictive value in identifying 30 d all-cause mortality of patients with AMI in ICU than the AG.
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