Evidence map›Paper›PMID 37118420›Full record

ReviewNature reviews. Chemistry2021

Interrupted reactions in chemical synthesis.

Vincent Trudel, Chieh-Hung Tien, Alina Trofimova, Andrei K Yudin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Rapid Access to Conjugated Z,Z,Z-Trienes.Angewandte Chemie (International ed. in English) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Non-symmetric stapling of native peptides.Nature reviews. Chemistry · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Iminologous epoxide ring-closure.Chemical science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vincent Trudel *Davenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.
Chieh-Hung Tien *Davenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-7859-5804
Alina TrofimovaDavenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.
Andrei K YudinDavenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto, Ontario, Canada. andrei.yudin@utoronto.ca.ORCID http://orcid.org/0000-0003-3170-9103

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interrupted reactions reroute established processes to new and often unanticipated end points. Of particular interest are the cases in which a known reactive intermediate takes on a new reaction pathway, either because this pathway is lower in energy or because the conventional pathway is no longer available. Through analysis of documented cases, we aim to dissect the known interrupted reactions and trace their mechanistic origins. As new chemical processes are being discovered at a seemingly ever-increasing pace, it is likely that new interrupted reactions will continue to emerge. Our hope is that the cases considered in this Review will help identify new classes of these fascinating transformations.

Identifiers

PMID37118420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.