ReviewNature reviews. Chemistry2021
Transient directing ligands for selective metal-catalysed C-H activation.
Review in Nature reviews. Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 141 citations in OpenAlex.
- Unlocking the Alkynyl Bromide Radical Anion With Alternating Current for Inverse Sonogashira C─H Coupling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Heterogeneous Palladium(0) Catalysts for C(spACS catalysis · 2026Article
- Manganese-CatalyzedACS omega · 2026Article
- Catalyst-Controlled Regiodivergent C-H Olefination of Furanyl Carbamates through a Rational Approach.JACS Au · 2026Article
- Vibrational snapshots of ultrafast C-H bond photoactivation inside a water-soluble nanocage.Chemical science · 2026Article
- One-Step Rh-Catalyzed Atom-Economical Cyclization of Acetophenones and Methyl Propiolate Affording Isoquinoline Derivatives.ACS omega · 2026Article
- Ligand assisted Co(ii) catalyzed direct C-H alkylation of aryl ketones with diverse alkyl halides.Chemical science · 2026Article
- Efficient one-pot quinoline derivative synthesis from acetophenone and allyl alcohols.RSC advances · 2026Article
- Monodentate Transient Directing Group Enabled Distal C─H Bond Functionalization in Ferrocenecarboxaldehyde.Chemistry, an Asian journal · 2026Article
- Migrating Group Strategy for Remote Functionalization of Seven-Membered Rings.Journal of the American Chemical Society · 2025Article
- Three distinct strategies lead to programmable aliphatic C-H oxidation in bicyclomycin biosynthesis.Nature communications · 2025Article
- Article
- Regioselective Aldehyde Decarbonylation through Palladium-Catalyzed Nitrile Boronic Acid Cross-Coupling.Synlett : accounts and rapid communications in synthetic organic chemistry · 2024Article
- Hydrogen bonding template enables remote meta-C-H alkenylation of nitroarenes with electron-deficient alkenes.Nature communications · 2024Article
- Switchable Site-Selective Benzanilide C(spMolecules (Basel, Switzerland) · 2024Article
- Atomically isolated Sb(CN)Science advances · 2024Article
- Palladium-CatalyzedMolecules (Basel, Switzerland) · 2024Article
- Dual Copper- and Aldehyde-Catalyzed Transient C-H Sulfonylation of Benzylamines.Organic letters · 2023Article
- Ruthenium-catalysed decarboxylative unsymmetric dualChemical science · 2023Article
- Phosphine Oxide-Promoted Rh(I)-Catalyzed C-H Cyclization of Benzimidazoles with Alkenes.Molecules (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
C-H activation is a 'simple-to-complex' transformation that nature has perfected over millions of years of evolution. Transition-metal-catalysed C-H activation has emerged as an expeditious means to expand the chemical space by introducing diverse functionalities. Notably, among the strategies to selectively cleave a particular C-H bond, the catalytic use of a small molecule as co-catalyst to generate a transient directing group, which provides a balance between step economy and chemical productivity, has gained immense attention in recent years. This allows one to convert a desired C-H bond irrespective of its geometrical or stereochemical configuration. This Review describes the various transient directing groups used in C-H activation and explains their mechanistic significance.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.