ReviewNature reviews. Chemistry2021
A single-molecule blueprint for synthesis.
Review in Nature reviews. Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Molecular Rectification: Mechanisms, Modulation Strategies, and Device Realization.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Scanning Tunneling Microscope-Based Break-Junction TechniqueA Tutorial.ACS physical chemistry Au · 2026Article
- Understanding single-molecule reactions using nanopore-based techniques.Nature chemistry · 2025Review
- Thioether-Linked Single-Molecule Junctions with Coinage Metal Contacts.Nano letters · 2025Article
- Single-Molecule Junctions Formed Using Different Electrode Metals Under an Inert Atmosphere.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Explore the Structural and Electronic Properties at the Organic/Organic Interfaces of Thiophene-Based Supramolecular Architectures.Nanomaterials (Basel, Switzerland) · 2025Article
- Structural and Electronic Properties of Thiophene-Based Supramolecular Architectures: Influence of the Underlying Metal Surfaces.Nanomaterials (Basel, Switzerland) · 2025Article
- Lewis-Acid Mediated Reactivity in Single-Molecule Junctions.Journal of the American Chemical Society · 2024Article
- Shape-persistent ladder molecules exhibit nanogap-independent conductance in single-molecule junctions.Nature chemistry · 2024Article
- α,ω-Alkanedibromides Form Low Conductance Chemisorbed Junctions with Silver Electrodes.Journal of the American Chemical Society · 2024Article
- Article
- Technologies for investigating single-molecule chemical reactions.National science review · 2024Review
- The role of halogens in Au-S bond cleavage for energy-differentiated catalysis at the single-bond limit.Nature communications · 2023Article
- Controlling piezoresistance in single molecules through the isomerisation of bullvalenes.Nature communications · 2023Article
- Research on Electric Field-Induced Catalysis Using Single-Molecule Electrical Measurement.Molecules (Basel, Switzerland) · 2023Review
- Advances in single-molecule junctions as tools for chemical and biochemical analysis.Nature chemistry · 2023Review
- Cleavage of non-polar C(spNature communications · 2023Article
- Precise tracking of tip-induced structural variation at the single-chemical-bond limit.Light, science & applications · 2023Article
- Scaling of quantum interference from single molecules to molecular cages and their monolayers.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemical reactions that occur at nanostructured electrodes have garnered widespread interest because of their potential applications in fields including nanotechnology, green chemistry and fundamental physical organic chemistry. Much of our present understanding of these reactions comes from probes that interrogate ensembles of molecules undergoing various stages of the transformation concurrently. Exquisite control over single-molecule reactivity lets us construct new molecules and further our understanding of nanoscale chemical phenomena. We can study single molecules using instruments such as the scanning tunnelling microscope, which can additionally be part of a mechanically controlled break junction. These are unique tools that can offer a high level of detail. They probe the electronic conductance of individual molecules and catalyse chemical reactions by establishing environments with reactive metal sites on nanoscale electrodes. This Review describes how chemical reactions involving bond cleavage and formation can be triggered at nanoscale electrodes and studied one molecule at a time.
Identifiers
37118183What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.