ReviewNature reviews. Chemistry2023
Miniaturizing chemistry and biology using droplets in open systems.
Review in Nature reviews. Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- High-speed photoacoustic laser streaming and on-demand fluid mixing in a microfluidic chip with carbon nanotube-based elastomers.Photoacoustics · 2026Article
- From flow to form: structuring and patterning hydrogels using microfluidic approaches.Lab on a chip · 2026Review
- Photo-Gated Corona Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Intelligent label-free droplet microfluidic sorting system for single-cell encapsulation and morphology-guided screening.Microsystems & nanoengineering · 2026Article
- Droplet-Engineered Scalable High-Throughput Perovskite Micropatterning for Next-Generation Optoelectronics.ACS nano · 2026Review
- Do-it-yourself protein arrays as high-throughput immunoassays enabled by confined droplets on patterned plasmonic chips.Nature communications · 2026Article
- Solvent Sustainability in Drug Discovery: Where Are We Now, and How Can We Improve?Journal of medicinal chemistry · 2025Review
- Lab on an end: Micromanipulation using the acoustohydrodynamic pillar array as an end effector.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Two-Layer Droplet Arrays Enable Dynamic Manipulation of Cell Microenvironment During High-Throughput Bacterial Cultivation.Small methods · 2025Article
- An integrated platform for liquid handling and cell imaging in life science applications.Nature communications · 2025Article
- Surface Friction Gradient-Mediated Directional Liquid Transport under Vibrational Activation.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Tunable, permanent and instantly available super-wettability states on metal surfaces by laser texturing and plasma coating.Scientific reports · 2025Article
- Cap-Drop: A Pre-Programmed, Self-Powered Capillary Microfluidic System for Passive Droplet Generation and 3D Cell Culture Modeling.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Topological elastic liquid diode.Science advances · 2025Article
- Regulation of Liquid Self-Transport Through Architectural-Thermal Coupling: Transitioning From Free Surfaces to Open Channels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets.ACS biomaterials science & engineering · 2025Article
- A Machine Vision Perspective on Droplet-Based Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Fully automated in vivo screening system for multi-organ imaging and pharmaceutical evaluation.Microsystems & nanoengineering · 2025Article
- Acoustofluidic Tweezers Integrated with Droplet Sensing Enable Multifunctional Closed-Loop Droplet Manipulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Are redox catalytic reaction rates accelerated in microdroplets on electrode surfaces?Journal of solid state electrochemistry : current research and development in science and technology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Open droplet microfluidic systems manipulate droplets on the picolitre-to-microlitre scale in an open environment. They combine the compartmentalization and control offered by traditional droplet-based microfluidics with the accessibility and ease-of-use of open microfluidics, bringing unique advantages to applications such as combinatorial reactions, droplet analysis and cell culture. Open systems provide direct access to droplets and allow on-demand droplet manipulation within the system without needing pumps or tubes, which makes the systems accessible to biologists without sophisticated setups. Furthermore, these systems can be produced with simple manufacturing and assembly steps that allow for manufacturing at scale and the translation of the method into clinical research. This Review introduces the different types of open droplet microfluidic system, presents the physical concepts leveraged by these systems and highlights key applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.