Evidence map›Paper›PMID 37117787›Full record

ArticleNature aging2023

Chronic in vivo imaging defines age-dependent alterations of neurogenesis in the mouse hippocampus.

Yicheng Wu, Sara Bottes, Roberto Fisch, Cinzia Zehnder, John Darby Cole, Gregor-Alexander Pilz, Fritjof Helmchen, Benjamin D Simons, Sebastian Jessberger

Open access · hybridAbstract read
In one paragraph

Article in Nature aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. DKK2 contributes to context discrimination and adult hippocampal neurogenesis by suppressing Wnt/PCP signaling.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  6. Article
  7. Review
  8. Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  9. Review
  10. Review
  11. Article
  12. Hallmarks of stem cell aging.Cell stem cell · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Experimental Neurogenesis in the Embryos of the Gecko Paroedura picta.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  18. Adolescent Alcohol and the Spectrum of Cognitive Dysfunction in Aging.Advances in experimental medicine and biology · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Yicheng WuLaboratory of Neural Plasticity, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-1202-4379
Sara BottesLaboratory of Neural Plasticity, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Roberto FischLaboratory of Neural Plasticity, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Cinzia ZehnderLaboratory of Neural Plasticity, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland.
John Darby ColeLaboratory of Neural Plasticity, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Gregor-Alexander PilzLaboratory of Neural Plasticity, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Fritjof HelmchenLaboratory of Neural Circuit Dynamics, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Benjamin D SimonsWellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0002-3875-7071
Sebastian JessbergerLaboratory of Neural Plasticity, Faculties of Medicine and Science, Brain Research Institute, University of Zurich, Zurich, Switzerland. jessberger@hifo.uzh.ch.ORCID 0000-0002-0056-8275
University of Zurich · CHWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

Medical Research Council MC_PC_17230
6 · The paper itself

Abstract

Neural stem cells (NSCs) generate new neurons throughout life in the mammalian hippocampus

Indexed as

Cognitive DysfunctionNeural Stem CellsAnimalsHippocampusMammalsMiceNeurogenesisNeurons

Identifiers

PMID37117787
PMCPMC10154232
OpenAlexW4321369888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.