Evidence map›Paper›PMID 37117318›Full record

ArticleLeukemia2023

Characterization of immune exhaustion and suppression in the tumor microenvironment of splenic marginal zone lymphoma.

Theodora Anagnostou, Zhi-Zhang Yang, Shahrzad Jalali, Hyo Jin Kim, Daniel P Larson, Xinyi Tang, Yue Yu, Joshua C Pritchett, Jose Villasboas Bisneto, Tammy L Price-Troska and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Leukemia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Mucosa-associated lymphoid tissue lymphoma with monoclonal T-cell expansion.Virchows Archiv : an international journal of pathology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Theodora Anagnostou *Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Zhi-Zhang Yang *Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA. yang.zhizhang@mayo.edu.ORCID http://orcid.org/0000-0002-1468-2300
Shahrzad JalaliDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Hyo Jin KimDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Daniel P LarsonDepartment of Pathology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-2938-922X
Xinyi TangDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-1889-4562
Yue YuDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Joshua C PritchettDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-6139-5526
Jose Villasboas BisnetoDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Tammy L Price-TroskaDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Patrizia MondelloDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Anne J NovakDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Stephen M AnsellDivision of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA. ansell.stephen@mayo.edu.ORCID http://orcid.org/0000-0003-1244-6758
Mayo Clinic in Arizona · USMayo Clinic · USMayo Clinic in Florida · US

Funding

The Role of Monocytes in non-Hodgkin LymphomaP50CA097274 · NCI · UNIVERSITY OF IOWA · PI LENTZ, STEVEN R · 2002 to 2021
$45.7M
NCI NIH HHS P50 CA097274
6 · The paper itself

Abstract

The role of the tumor microenvironment (TME) and intratumoral T cells in splenic marginal zone lymphoma (sMZL) is largely unknown. In the present study, we evaluated 36 sMZL spleen specimens by single cell analysis to gain a better understanding of the TME in sMZL. Using mass cytometry (CyTOF), we observed that the TME in sMZL is distinct from that of control non-malignant reactive spleen (rSP). We found that the number of T

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellLymphomaLymphoma, B-Cell, Marginal ZoneSplenic NeoplasmsCD8-Positive T-LymphocytesHumansTumor Microenvironment

Identifiers

PMID37117318
OpenAlexW4367296843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.