ArticleScientific reports2023
Increased incidence of vertebral fractures in German adults from 2009 to 2019 and the analysis of secondary diagnoses, treatment, costs, and in-hospital mortality.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 42 citations in OpenAlex.
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- The fourth column in thoracic vertebral fractures: concomitant thoracic cage injuries and mortality in 27,814 inpatient cases from the german national DRG database.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Multilevel Lumbar CT Attenuation Beyond L1: Comparison with QCT-Derived Volumetric Bone Mineral Density and Prevalent Fragility Fracture Status in a Diagnostic Referral Cohort.Diagnostics (Basel, Switzerland) · 2026Article
- Potential change in healthcare costs of implementing artificial intelligence for detecting cervical spine fractures on CT: an early health technology assessment.European radiology · 2026Article
- Vertebral-level discrimination of incidental vertebral fractures using volumetric BMD, texture features, and finite element-derived fracture load: an exploratory study.Skeletal radiology · 2026Article
- Return to Work After Isolated Spinal Injury: Rates, Predictors, and Implications for Occupational Reintegration.Journal of occupational rehabilitation · 2026Article
- Tobacco smoke exposure and spine fracture risk in US adults: A cross-sectional analysis of the National Health and Nutrition Examination Survey 1999-2010, 2013-2014, 2017-2020.Tobacco induced diseases · 2026Article
- Medical treatment of osteoporosis in osteoporotic vertebral fractures - Results from the prospective EOFTT multicenter study.Brain & spine · 2026Article
- Challenges and solutions in determining urolithiasis caseloads using the digital infrastructure of a clinical data warehouse.PloS one · 2026Article
- A 3D-printed hybrid vertebroplasty, kyphoplasty and screw augmentation teaching model simulating high and low bone mineral densities.Brain & spine · 2026Article
- OF-score for osteoporotic thoracolumbar fractures- which parameter is decisive for the therapy decision? - a prospective multicentric cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Trends of incidence and 1-year mortality of vertebral fractures in Korea using nationwide claims data.Archives of osteoporosis · 2025Article
- Deep learning-driven incidental detection of vertebral fractures in cancer patients: advancing diagnostic precision and clinical management.La Radiologia medica · 2025Article
- The prevention of osteoporotic vertebral fractures in eastern and in western countries.Bone reports · 2025Review
- Fracture analysis of working-age adults in Turkey: a 7-year national registry study.BMC musculoskeletal disorders · 2025Article
- Trends in prevalence of spine fractures and risk factors in spine fractures among US adults, 1999-2018.Scientific reports · 2025Article
- The impact of preoperative handgrip strength on postoperative outcomes following transforaminal lumbar interbody fusion.Journal of orthopaedic surgery and research · 2025Observational
- Falling rates but projected rising numbers of fractures in elderly Norwegians: a study of fracture rates in the Norwegian patient registry from 2010 to 2021, extrapolated to 2041.Acta orthopaedica · 2025Article
- Opportunistic Osteoporosis Assessment and Fracture Risk Determination Using Cancellous Density Measurement in Hounsfield Units of Native Lumbar Computed Tomography Images-A Comparative Study with Conventional Bone Density Evaluation.Journal of clinical medicine · 2025Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
The aim of this cross-sectional study was to present the nationwide rates of hospitalized patients with vertebral fractures over one decade and to comprehensively analyze the treatment characteristics and direct costs incurred in 2019. Therefore, the trends in the incidence rate were quantified based on annual ICD-10 diagnosis codes from all German medical facilities between 2009 and 2019, provided by the Federal Statistical Office (Destatis). The ICD-10 Codes "S12.0-2; S22.0-; S32.0-, and S32.1-2" were evaluated. The relative change from 2009 through 2019 was determined. Using data from the Institute for Hospital Remuneration Systems (InEK) for 2019 the secondary diagnoses, OPS-codes, intensive care unit (ICU) treatment, in-hospital mortality, the proportion of G-DRGs and cumulative costs were evaluated. The documented number of vertebral fractures increased by 45.6% between 2009 and 2019 to an incidence of 150.7 per 100,000 inhabitants. The lumbar spine was most commonly affected with an incidence of 70.5/100,000 inhabitants in 2019 (46.8% of all vertebral fractures). The highest increases were seen in the numbers of subaxial cervical fractures (+ 121.2%) and sacral fractures (+ 306.6%). Of all vertebral fractures in 2019, 63.7% were diagnosed in women and 69.0% in patients aged 70 years or older. Osteoporosis was documented in 17.9% of cases as a concomitant diagnosis. In 10.1% of all cases, an ICU treatment was documented. The in-hospital mortality was 2.0% in 2019. I68D was the most frequently used G-DRG code, accounting for 33.3% of cases. The total direct costs for inpatient treatment in 2019 amounted to €589,205,715. The evaluation of 955,091 vertebral fractures showed a sharp increase in the nation-wide incidence rate. The presented age and sex distribution, the comorbidity profile and the in-hospital mortality rate indicate the importance of comprehensive geriatric assessment and emphasize the need for spinal care centers to be established.
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