Evidence map›Paper›PMID 37117139›Full record

ArticleUltrasound in medicine & biology2023

Assessing Enhanced Acoustic Absorption From Sonosensitive Perfluorocarbon Emulsion With Magnetic Resonance-Guided High-Intensity Focused Ultrasound and a Percolated Tissue-Mimicking Flow Phantom.

Ryan Holman, Pauline C Guillemin, Orane Lorton, Stéphane Desgranges, Christiane Contino-Pépin, Rares Salomir

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasound in medicine & biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Ryan HolmanImage Guided Interventions Laboratory, Department of Radiology, University of Geneva, Geneva, Switzerland. Electronic address: rholman2@bwh.harvard.edu.
Pauline C GuilleminImage Guided Interventions Laboratory, Department of Radiology, University of Geneva, Geneva, Switzerland.
Orane LortonImage Guided Interventions Laboratory, Department of Radiology, University of Geneva, Geneva, Switzerland.
Stéphane DesgrangesEquipe Systèmes Amphiphiles bioactifs et Formulations Eco-compatibles, Unité Propre de Recherche et d'Innovation (UPRI), Avignon University, Avignon, France.
Christiane Contino-PépinEquipe Systèmes Amphiphiles bioactifs et Formulations Eco-compatibles, Unité Propre de Recherche et d'Innovation (UPRI), Avignon University, Avignon, France.
Rares SalomirImage Guided Interventions Laboratory, Department of Radiology, University of Geneva, Geneva, Switzerland; Radiology Division, University Hospitals of Geneva, Geneva, Switzerland.
University of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSonosensitive high-boiling point perfluorocarbon F

methodsIn this study, similar perfluorocarbon emulsions were circulated at incremental concentrations of 0.07, 0.13, 0.19 and 0.25% v:v through a percolated turbulent flow phantom, more representative of the biological tissue than a laminar flow phantom. The concentrations represent the droplet content in only the perfused fluid, rather than the droplet concentration throughout the entire cross-section. The temperature was measured with magnetic resonance thermometry, during focused ultrasound sonications of 67 W, 95% duty cycle and 33 s duration. These were used in Bioheat equation simulations to investigate in silico the thermal phenomena. The temperature change was compared with the control condition by circulating de-gassed and de-ionized water through the flow phantom without droplets.

resultsWith these 1.24 µm diameter droplets at 0.25% v:v, the acoustic absorption coefficient increased from 0.93 ± 0.05 at 0.0% v:v to 1.82 ± 0.22 m

conclusionThe results further support previously reported thermal enhancement with F

Indexed as

FluorocarbonsHigh-Intensity Focused Ultrasound AblationAcousticsAnimalsEmulsionsHydrocarbons, BrominatedMagnetic Resonance ImagingMagnetic Resonance SpectroscopySwineEmulsionsFluorocarbonsHydrocarbons, BrominatedperflubronFlow phantomHigh-intensity focused ultrasoundInterventional radiologyMagnetic resonance imagingPerfluorocarbonsSonosensitizers

Identifiers

PMID37117139
PMCPMC10229106
OpenAlexW4367042687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.