Evidence map›Paper›PMID 37117016›Full record

ArticleCold Spring Harbor protocols2023

CRISPR Gene Editing of Virulent Bacteriophage ICP1.

Andrew Camilli

Abstract read
In one paragraph

Article in Cold Spring Harbor protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. CRISPR Gene Editing of a Virulent Bacteriophage.Cold Spring Harbor protocols · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Andrew CamilliDepartment of Molecular Biology and Microbiology, Tufts University, School of Medicine, Boston, Massachusetts 02067, USA andrew.camilli@tufts.edu.

Funding

Phage Resistance in Emergent Vibrio cholerae and Phage Prophylaxis of CholeraR37AI055058 · NIAID · TUFTS UNIVERSITY BOSTON · PI Andrew Camilli · 2020 to 2026
$3.4M
NIAID NIH HHS R37 AI055058
6 · The paper itself

Abstract

Tools for site-directed mutagenesis of virulent bacteriophages (phages; viruses of bacteria) have traditionally lagged those for bacteria, hindering their study. CRISPR gene editing represents a new and highly efficient method for editing virulent phage genomes. Here, I describe methods for using CRISPR gene editing for site-directed mutagenesis of ICP1, a virulent phage of

Identifiers

PMID37117016
PMCPMC10613450

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.