Evidence map›Paper›PMID 37117011›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Control of Synaptic Levels of Nicotinic Acetylcholine Receptor by the Sequestering Subunit Dα5 and Secreted Scaffold Protein Hig.

Minoru Nakayama, Osamu Nishimura, Yuhi Nishimura, Miwa Kitaichi, Shigehiro Kuraku, Masaki Sone, Chihiro Hama

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Molecular organization of central cholinergic synapses.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Minoru NakayamaFaculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan.
Osamu NishimuraLaboratory for Phyloinformatics, RIKEN Center for Biosystems Dynamics Research, RIKEN, Kobe 650-0047, Japan.
Yuhi NishimuraFaculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan.
Miwa KitaichiFaculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan.
Shigehiro KurakuLaboratory for Phyloinformatics, RIKEN Center for Biosystems Dynamics Research, RIKEN, Kobe 650-0047, Japan.
Masaki SoneFaculty of Science, Toho University, Funabashi 274-8510, Japan.
Chihiro HamaFaculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan hama@cc.kyoto-su.ac.jp.ORCID 0000-0002-4158-719X
Kyoto Sangyo University · JPRIKEN Center for Biosystems Dynamics Research · JPToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presentation of nicotinic acetylcholine receptors (nAChRs) on synaptic membranes is crucial for generating cholinergic circuits, some of which are associated with memory function and neurodegenerative disorders. Although the physiology and structure of nAChR, a cation channel comprising five subunits, have been extensively studied, little is known about how the receptor levels in interneuronal synapses are determined and which nAChR subunits participate in the regulatory process in cooperation with synaptic cleft matrices and intracellular proteins. By a genetic screen of

Indexed as

Drosophila ProteinsReceptors, NicotinicAnimalsCholinergic AgentsDrosophilaFemaleMaleNerve Tissue ProteinsSynaptic TransmissionCholinergic AgentsDrosophila Proteinshig protein, DrosophilanAChRalpha5 protein, DrosophilaNerve Tissue ProteinsReceptors, Nicotinicacetylcholineacetylcholine receptorDrosophilaHigsynapsesynaptic cleft

Identifiers

PMID37117011
PMCPMC10255049
OpenAlexW4367309069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.