Evidence map›Paper›PMID 37116993›Full record

Observational studyBMJ open2023

Resting heart rate and risk of atrial fibrillation in Chinese general population: Kailuan prospective cohort study.

Ziwei Hou, Mao Xiang Zhao, Yizhen Sun, Sijing Zhang, Siyu Yao, Chi Wang, Miao Wang, Cuijuan Yun, Hao Xue, Shouling Wu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ziwei HouDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Mao Xiang ZhaoDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0001-7027-5913
Yizhen SunDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Sijing ZhangClinical medicine, Nankai University, Tianjin, China.
Siyu YaoDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Chi WangDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Miao WangDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Cuijuan YunClinical medicine, Nankai University, Tianjin, China.
Hao XueDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China xuehaoxh301@163.com.ORCID 0000-0001-5915-4811
Shouling WuDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Chinese PLA General Hospital · CNNankai University · CNNorth China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious research has shown an association of higher heart rate with an increased risk of atrial fibrillation (AF). However, the relationship between resting heart rate (RHR) and AF is unknown. The aim of this study was to investigate the association between RHR and AF in the general population of China.

designProspective observational cohort study.

settingCommunity based.

participantsA total of 46 126 individuals from the Kailuan study who participated in the first three surveys (2006/2007, 2008/2009 and 2010/2011) and were followed up at 2-year intervals were enrolled. PRIMARY OUTCOME MEASURES: The association between RHR and risk of incident AF was evaluated using Cox proportional hazards regression and restricted cubic spline models.

resultsTwo hundred and forty-one individuals (0.52%) developed AF during 7.5 years of follow-up. After adjustment for age, sex, low-density and high-density lipoprotein, physical activity, alcohol consumption, smoking status, body mass index, mean systolic blood pressure, and history of diabetes and hypertension, the HRs were 2.32 (95% CI 1.45 to 3.72) for an RHR <60 beats/min and 2.80 (1.13 to 6.94) for an RHR ≥100 beats/min in comparison with an RHR of 70-80 beats/min. Restricted cubic spline models revealed a U-shaped relationship between RHR and incident AF.

conclusionThese findings indicate that RHR and incident AF have a U-shaped relationship in the Chinese general population. Both lower and higher RHRs were associated with an increased risk of AF.

Indexed as

Atrial FibrillationEast Asian PeopleHeart RateHumansProspective StudiesRisk FactorsAdult cardiologyCardiologyRisk management

Identifiers

PMID37116993
PMCPMC10151892
OpenAlexW4367309394

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.