Evidence map›Paper›PMID 37116856›Full record

ArticleOsteoarthritis and cartilage2023

Persistent underloading of patellofemoral joint following hamstring autograft ACL reconstruction is associated with cartilage health.

Tzu-Chieh Liao, Alyssa Bird, Michael A Samaan, Valentina Pedoia, Sharmila Majumdar, Richard B Souza

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoarthritis and cartilage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tzu-Chieh LiaoDepartment of Physical Therapy, University of Michigan-Flint, Flint, MI, USA; Department of Radiology, University of Michigan, Ann Arbor, MI, USA. Electronic address: jenliao@umich.edu.
Alyssa BirdDepartment of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, CA, USA.
Michael A SamaanDepartment of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY, USA.
Valentina PedoiaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.
Sharmila MajumdarDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.
Richard B SouzaDepartment of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, CA, USA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USUniversity of Kentucky · USUniversity of Michigan · US

Funding

Translation of Quantitative Imaging in OsteoarthritisP50AR060752 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOUZA, RICHARD BRIAN · 2011 to 2015
$6.2M
Mentoring Biomechanics Research in OsteoarthritisK24AR072133 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Richard Brian Souza · 2018 to 2026
$1.5M
Deep Learning for Characterizing Knee Joint Degeneration Predicting Progression of Osteoarthritis and Total Knee ReplacementR61AR073552 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA, PEDOIA, VALENTINA · 2018 to 2019
$871k
Hox genes regulate functionally distinct, regionally restricted MSC populationsR61AR073523 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI WELLIK, DENEEN M · 2018 to 2019
$761k
Multidimensional MRI-based Non-Euclidean Deep Learning to Study OsteoarthritisR00AR070902 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PEDOIA, VALENTINA · 2018 to 2020
$747k
Quantifying the Mechanism and Impact of Hip Extensor Muscle Dysfunction During Aerobic Exercise in Hip OsteoarthritisK01AG073698 · NIA · UNIVERSITY OF KENTUCKY · PI Michael A Samaan · 2022 to 2026
$612k
NIAMS NIH HHS K24 AR072133NIAMS NIH HHS P50 AR060752NIAMS NIH HHS R00 AR070902NIAMS NIH HHS R61 AR073523NIAMS NIH HHS R61 AR073552NIA NIH HHS K01 AG073698
6 · The paper itself

Abstract

objectiveTo determine the longitudinal changes of patellofemoral joint (PFJ) contact pressure following anterior cruciate ligament reconstruction (ACLR). To identify the associations between PFJ contact pressure and cartilage health.

designForty-nine subjects with hamstring autograft ACLR (27 males; age 28.8 [standard deviation, 8.3] years) and 19 controls (12 males; 30.7 [4.6] years) participated. A sagittal plane musculoskeletal model was used to estimate PFJ contact pressure. A combined T

resultsNo changes in peak PFJ contact pressure were found within ACLR knees over 3 years (preoperative to 3 years, 0.36 [CI, -0.08, 0.81] MPa), but decreased over time in the contralateral knees (0.75 [0.32, 1.18] MPa). When compared to the controls, ACLR knees exhibited lower PFJ contact pressure at all time points (at baseline, -0.64 [-1.25, -0.03] MPa). Within ACLR knees, lower PFJ contact pressure at 6 months was associated with elevated T

conclusionsUnderloading of the PFJ following ACLR persists for up to 3 years and has concurrent and future consequences in cartilage health. The non-surgical knees exhibited normal contact pressure initially but decreased over time achieving limb symmetry.

Indexed as

Anterior Cruciate Ligament InjuriesCartilage, ArticularPatellofemoral JointAdultAutograftsHumansKneeKnee JointMagnetic Resonance ImagingMaleAnterior cruciate ligament reconstructionCartilage relaxation timesContact pressureHamstring autograftOsteoarthritis

Identifiers

PMID37116856
PMCPMC11167283
OpenAlexW4367056907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.