ArticleCancer cell2023
Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer.
Open access · hybridAbstract readLetter
In one paragraph
Article in Cancer cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Improved Resolution of Influenza Vaccination Responses With High-Throughput Live Virus Microneutralisation.Influenza and other respiratory viruses · 2025Article
- Case Report: Persistent COVID-19 in a fully vaccinated Japanese man being treated with rituximab and epcoritamab for diffuse large B-cell lymphoma.Frontiers in medicine · 2025Article
- Clinical Efficacy of Imdevimab/Casirivimab for Persistent Omicron SARS-CoV-2 Infection in Patients with Hematological Malignancies.Internal medicine (Tokyo, Japan) · 2024Article
- Sotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients.Med (New York, N.Y.) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
67 authors at 4 institutions in 3 countries.
Mary Y WuCOVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
Scott T C ShepherdCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
Annika FendlerSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Department of Urology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
Edward J CarrCell Biology of Infection Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Division of Medicine, University College London, London NW1 2PG, UK.
Lewis AuCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK; Department of Medical Oncology, Peter MacCallum Cancer Centre, VIC 3010, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, VIC 3010, Melbourne, Australia.
Ruth HarveyWorldwide Influenza Centre, The Francis Crick Institute, London NW1 1AT, UK.
Giulia DowgierCOVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
Agnieszka HobbsCOVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
Lou S HermanCOVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
Martina RagnoCOVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
Lorin AdamsWorldwide Influenza Centre, The Francis Crick Institute, London NW1 1AT, UK.
Andreas M SchmittSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Zayd TippuCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
Benjamin ShumCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
Sheima FaragSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Aljosja RogiersSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Nicola O'ReillyWorldwide Influenza Centre, The Francis Crick Institute, London NW1 1AT, UK.
Philip BawumiaHuman Biology Science and Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
Callie SmithHuman Biology Science and Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
Eleanor CarlyleSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Kim EdmondsSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Lyra Del RosarioSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Karla LingardSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Mary MangwendeSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Lucy HoltSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Hamid AhmodSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Justine KortewegSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Tara FoleySkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Taja BarberCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Stephanie HepworthCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Andrea Emslie-HenryCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Niamh Caulfield-LynchCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Fiona ByrneCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Daqi DengCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Bryan WilliamsSchool of Life and Medical Sciences, University College London, 235 Euston Road, London NW1 2BU, UK; University College London Hospitals NHS Foundation Trust Biomedical Research Centre, London WC1E 6BT, UK.
Michael BrownUniversity College London Hospitals NHS Foundation Trust Biomedical Research Centre, London WC1E 6BT, UK; Clinical Research Department, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
Simon CaidanSafety, Health & Sustainability, The Francis Crick Institute, London NW1 1AT, UK.
Mike GavrielidesScientific Computing Scientific Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
James I MacRaeMetabolomics Scientific Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
Gavin KellyDepartment of Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK.
Kema PeatSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Denise KellySkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Aida MurraSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Kayleigh KellySkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Molly O'FlahertySkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Sanjay PopatLung Unit, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Nadia YousafLung Unit, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Shaman JhanjiAnaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Kate TathamAnaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
David CunninghamGastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, SM2 5PT, UK.
Nicholas Van AsClincal Oncology Unit, The Royal Marsden NHS Foundation Trust, London NW1 1AT, UK.
Kate YoungSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Andrew J S FurnessSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
Lisa PickeringSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Rupert BealeCell Biology of Infection Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Division of Medicine, University College London, London NW1 2PG, UK.
Charles SwantonCancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London NW1 1AT, UK; University College London Cancer Institute, London WC1E 6DD, UK.
Sonia GandhiNeurodegeneration Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.
Steve GamblinStructural Biology of Disease Processes Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
David L V BauerRNA Virus Replication Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
George KassiotisRetroviral Immunology Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Michael HowellHigh Throughput Screening Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Susanna WalkerAnaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
Emma NicholsonHaemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Haemato-oncology Unit, The Institute of Cancer Research, London SW7 3RP, UK.
James LarkinSkin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
Emma C WallSchool of Life and Medical Sciences, University College London, 235 Euston Road, London NW1 2BU, UK; The Francis Crick Institute, London NW1 1AT, UK. Electronic address: emma.wall@crick.ac.uk.
Samra TurajlicCancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK. Electronic address: samra.turajlic@crick.ac.uk.
CAPTURE consortium
Royal Marsden NHS Foundation Trust · GBThe Francis Crick Institute · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity of London · GB
Funding
Cancer Research UK 18176Cancer Research UK 29911Medical Research Council MR/W005611/1Medical Research Council MR/X006751/1Wellcome Trust FC001002Wellcome Trust FC001030Wellcome Trust FC001078Wellcome Trust FC001099Wellcome Trust FC001169Wellcome Trust FC001218Wellcome Trust FC001988Wellcome Trust FC011104
Abstract
Wu et al. report that patients with hematologic malignancies have reduced immunity against SARS-CoV-2 Omicron subvariants and Sotrovimab retains neutralizing capacity against all tested Omicron subvariants.
Indexed as
COVID-19Hematologic NeoplasmsNeoplasmsAntibodies, Monoclonal, HumanizedAntibodies, NeutralizingHumansSARS-CoV-2Antibodies, Monoclonal, HumanizedAntibodies, Neutralizingsotrovimab
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.