Evidence map›Paper›PMID 37116214›Full record

ArticleJournal of chemical theory and computation2023

Molecular Dynamics Simulations of Ion Permeation in Human Voltage-Gated Sodium Channels.

Giulio Alberini, Sergio Alexis Paz, Beatrice Corradi, Cameron F Abrams, Fabio Benfenati, Luca Maragliano

Open access · hybridAbstract read
In one paragraph

Article in Journal of chemical theory and computation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Preorganized Electric Fields in Voltage-Gated Sodium Channels.Chembiochem : a European journal of chemical biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Constitutive opening of the Kv7.2 pore activation gate causesProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Ion and water permeation through claudin-10b and claudin-15 paracellular channels.Computational and structural biotechnology journal · 2024
    Article
  11. Article
  12. Review
  13. Plasticity of the selectivity filter is essential for permeation in lysosomal TPC2 channels.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Giulio AlberiniCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy.
Sergio Alexis PazDepartamento de Química Teórica y Computacional, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, X5000HUA Córdoba, Argentina.ORCID 0000-0001-9471-0502
Beatrice CorradiCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy.
Cameron F AbramsDepartment of Chemical and Biological Engineering, Drexel University, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0002-1240-0816
Fabio BenfenatiCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy.ORCID 0000-0002-0653-8368
Luca MaraglianoCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy.ORCID 0000-0002-5705-6967
Italian Institute of Technology · ITConsejo Nacional de Investigaciones Científicas y Técnicas · ARDrexel University · USMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent determination of cryo-EM structures of voltage-gated sodium (Na

Indexed as

Molecular Dynamics SimulationVoltage-Gated Sodium ChannelsBacteriaHumansIonsLysineIonsLysineVoltage-Gated Sodium Channels

Identifiers

PMID37116214
PMCPMC10210251
OpenAlexW4367302755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.