Evidence map›Paper›PMID 37116162›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2023

Artificial Intelligence Role in Subclassifying Cytology of Thyroid Follicular Neoplasm.

Mona Mohamed Aly Alabrak, Mohammad Megahed, Asmaa Abdulaziz Alkhouly, Ammar Mohammed, Habiba Elfandy, Neveen Tahoun, Hoda Abdel-Raouf Ismail

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Article in Asian Pacific journal of cancer prevention : APJCP, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

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8citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Mona Mohamed Aly AlabrakDepartment of Pathology, National Cancer Institute, Cairo University, Egypt.ORCID 0000-0002-6620-3738
Mohammad MegahedDepartment of computer science, Faculty of Graduate Studies for Statistical Research, Cairo University, Egypt.
Asmaa Abdulaziz AlkhoulyDepartment of computer science, Faculty of Graduate Studies for Statistical Research, Cairo University, Egypt.
Ammar MohammedDepartment of computer science, Faculty of Graduate Studies for Statistical Research, Cairo University, Egypt.
Habiba ElfandyDepartment of Pathology, National Cancer Institute, Cairo University, Egypt.
Neveen TahounDepartment of Pathology, National Cancer Institute, Cairo University, Egypt.
Hoda Abdel-Raouf IsmailDepartment of Pathology, National Cancer Institute, Cairo University, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFine needle aspiration cytology has higher sensitivity and predictive value for diagnosis of thyroid nodules than any other single diagnostic methods.  In the Bethesda system for reporting thyroid, the category IV, encompasses both adenoma and carcinoma, but it is not possible to differentiate both lesions in the cytology practice and can be only differentiated after resection. In this work, we aim at exploring the ability of a convolutional neural network (CNN) model to sub-classifying cytological images of Bethesda category IV diagnosis into follicular adenoma and follicular carcinoma.

methodsWe used a cohort of cytology cases n= 43 with extracted images n= 886 to train CNN model aiming to sub-classify follicular neoplasm (Bethesda category IV) into either follicular adenoma or follicular carcinoma.

resultIn our study, the model subclassification of follicular neoplasm into follicular adenoma (n = 28/43, images n = 527/886) from follicular carcinoma (n = 15/43, images n= 359/886), has achieved an accuracy of 78%, with a sensitivity of 88.4%, and a specificity of 64% and an area under the curve (AUC) score of 0.87 for each of follicular adenoma and follicular carcinoma.

conclusionOur CNN model has achieved high sensitivity in recognizing follicular adenoma amongest cytology smears of follciualr neoplasms, thus it can be used as an ancillary technique in the subcalssification of Bethesda Iv category cytology smears.

Indexed as

Adenocarcinoma, FollicularAdenomaCarcinomaThyroid NeoplasmsThyroid NoduleArtificial IntelligenceHumansAIconvolutional neural networkcytopathologyDiagnosisThyroid gland

Identifiers

PMID37116162
PMCPMC10352752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.