Evidence map›Paper›PMID 37115521›Full record

ReviewChemical reviews2023

Photobiocatalytic Strategies for Organic Synthesis.

Megan A Emmanuel, Sophie G Bender, Catherine Bilodeau, Jose M Carceller, Jacob S DeHovitz, Haigen Fu, Yi Liu, Bryce T Nicholls, Yao Ouyang, Claire G Page and 9 more

Abstract readReview
In one paragraph

Review in Chemical reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Nanomaterial Integration at Liquid-Liquid Interfaces for Green Catalysis.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Toward Sustainability: Intensification of Light-Driven Whole Cell Biocatalysis.Chembiochem : a European journal of chemical biology · 2026
    Review
  13. Article
  14. Article
  15. Biocatalytic Radical C(spResearch square · 2026
    Article
  16. Pyridoxal 5'-Phosphate-Dependent Enzymatic Decarboxylative Annulation.Journal of the American Chemical Society · 2026
    Article
  17. Article
  18. Photoenzymatic CspProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Megan A EmmanuelDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Sophie G BenderDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Catherine BilodeauDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Jose M CarcellerDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Jacob S DeHovitzDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Haigen FuDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Yi LiuDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Bryce T NichollsDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Yao OuyangDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Claire G PageDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Tianzhang QiaoDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Felix C RapsDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Damien R SoriguéDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Shang-Zheng SunDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Joshua Turek-HermanDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Yuxuan YeDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Ariadna Rivas-SouchetDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Jingzhe CaoDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Todd K HysterDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.ORCID 0000-0003-3560-355X

Funding

Hyster (Rivas-Souchet) Diversity SupplementR01GM127703 · NIGMS · PRINCETON UNIVERSITY · PI Todd Kurt Hyster · 2018 to 2026
$2.9M
NIGMS NIH HHS R01 GM127703
6 · The paper itself

Abstract

Biocatalysis has revolutionized chemical synthesis, providing sustainable methods for preparing various organic molecules. In enzyme-mediated organic synthesis, most reactions involve molecules operating from their ground states. Over the past 25 years, there has been an increased interest in enzymatic processes that utilize electronically excited states accessed through photoexcitation. These photobiocatalytic processes involve a diverse array of reaction mechanisms that are complementary to one another. This comprehensive review will describe the state-of-the-art strategies in photobiocatalysis for organic synthesis until December 2022. Apart from reviewing the relevant literature, a central goal of this review is to delineate the mechanistic differences between the general strategies employed in the field. We will organize this review based on the relationship between the photochemical step and the enzymatic transformations. The review will include mechanistic studies, substrate scopes, and protein optimization strategies. By clearly defining mechanistically-distinct strategies in photobiocatalytic chemistry, we hope to illuminate future synthetic opportunities in the area.

Indexed as

BiocatalysisChemistry Techniques, Synthetic

Identifiers

PMID37115521
PMCPMC10905417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.