Evidence map›Paper›PMID 37115511›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2023

Time to Introduce Nerve Density in Cancer Histopathologic Assessment.

Hubert Hondermarck, Chen Chen Jiang

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Tumor Innervation: From Bystander to Emerging Therapeutic Target for Cancer.International journal of molecular sciences · 2025
    Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Hubert HondermarckSchool of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0003-3807-2985
Chen Chen JiangSchool of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0001-9133-6391

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The density of nerves in the tumor microenvironment is increasingly reported to be associated with worse clinical outcome in various cancers. Therefore, it is time to consider the assessment of nerve density in clinical cancer pathology, and interestingly, the development of artificial intelligence may facilitate this clinical translation. See related article by Perez-Pacheco et al., p. 2501.

Indexed as

Mouth NeoplasmsNerve TissueArtificial IntelligenceHumansTumor Microenvironment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.