Evidence map›Paper›PMID 37115010›Full record

ArticleBiochemistry2023

Ajay Sharma, Chris Whittington, Mohammed Jabed, S Gage Hill, Anastasiia Kostenko, Tao Yu, Pengfei Li, Peter E Doan, Brian M Hoffman, Adam R Offenbacher

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. OJournal of the American Chemical Society · 2025
    Article
  3. Article
  4. Terminal Hydride Complex of High-Spin Mn.Journal of the American Chemical Society · 2024
    Article
  5. Impact ofBiochemistry · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ajay SharmaDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-0829-6753
Chris WhittingtonDepartment of Chemistry, East Carolina University, Greenville, North Carolina 27858, United States.
Mohammed JabedDepartment of Chemistry, University of North Dakota, Grand Forks, North Dakota 58202, United States.ORCID 0000-0001-8552-0301
S Gage HillDepartment of Chemistry, East Carolina University, Greenville, North Carolina 27858, United States.ORCID 0000-0002-0650-2293
Anastasiia KostenkoDepartment of Chemistry, East Carolina University, Greenville, North Carolina 27858, United States.
Tao YuDepartment of Chemistry, University of North Dakota, Grand Forks, North Dakota 58202, United States.ORCID 0000-0002-0738-425X
Pengfei LiDepartment of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois 60660, United States.ORCID 0000-0002-2572-5935
Peter E DoanDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Brian M HoffmanDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-3100-0746
Adam R OffenbacherDepartment of Chemistry, East Carolina University, Greenville, North Carolina 27858, United States.ORCID 0000-0001-6990-7178
East Carolina University · USNorthwestern University · USUniversity of North Dakota · USLoyola University Chicago · US

Funding

Coboglobins-Cobalt-Substituted Hemoglobins and MyoglobinR01GM111097 · NIGMS · NORTHWESTERN UNIVERSITY · PI HOFFMAN, BRIAN M · 2014 to 2025
$6.7M
NIGMS NIH HHS R01 GM111097
6 · The paper itself

Abstract

Lipoxygenase (LOX) enzymes produce important cell-signaling mediators, yet attempts to capture and characterize LOX-substrate complexes by X-ray co-crystallography are commonly unsuccessful, requiring development of alternative structural methods. We previously reported the structure of the complex of soybean lipoxygenase, SLO, with substrate linoleic acid (LA), as visualized through the integration of

Indexed as

LipoxygenaseMolecular Dynamics SimulationAnimalsElectron Spin Resonance SpectroscopyHydrogenLinoleic AcidHydrogenLinoleic AcidLipoxygenase

Identifiers

PMID37115010
PMCPMC10704959
OpenAlexW4367298400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.