Evidence map›Paper›PMID 37114796›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIR-I/II Fluorophores.

Zhiqiang Mao, Hyeonji Rha, Jungryun Kim, Xinru You, Fan Zhang, Wei Tao, Jong Seung Kim

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Fluorescent small molecule donors.Chemical Society reviews · 2024
    Review
  5. Article
  6. THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIR-I/II Fluorophores.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiqiang MaoCollege of Health Science and Engineering, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China.
Hyeonji RhaDepartment of Chemistry, Korea University, Seoul, 02841, South Korea.
Jungryun KimDepartment of Chemistry, Korea University, Seoul, 02841, South Korea.
Xinru YouCenter for Nanomedicine and Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Fan ZhangCollege of Health Science and Engineering, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China.
Wei TaoCenter for Nanomedicine and Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.ORCID 0000-0002-4277-3728
Jong Seung KimDepartment of Chemistry, Korea University, Seoul, 02841, South Korea.

Funding

National Natural Science Foundation of China 21904031National Natural Science Foundation of China 22174034National Research Foundation of Korea 2018R1A3B1052702Natural Science Foundation of Hubei Province 2021CFB305
6 · The paper itself

Abstract

Near-infrared fluorescence imaging is vital for exploring the biological world. The short emissions (<650 nm) and small Stokes shifts (<30 nm) of current xanthene dyes obstruct their biological applications since a long time. Recently, a potent and universal THQ structural modification technique that shifts emission to the NIR-I/II range and enables a substantial Stokes shift (>100 nm) for THQ-modified xanthene dyes is established. Thus, a timely discussion of THQ-xanthene and its applications is extensive. Hence, the advent, working principles, development trajectory, and biological applications of THQ-xanthene dyes, especially in the fields of fluorescence probe-based sensing and imaging, cancer theranostics, and super-resolution imaging, are introduced. It is envisioned that the THQ modification tactic is a simple yet exceptional approach to upgrade the performance of conventional xanthene dyes. THQ-xanthene will advance the strides of xanthene-based potentials in early fluorescent diagnosis of diseases, cancer theranostics, and imaging-guided surgery.

Indexed as

Fluorescent DyesXanthenesBenzopyransOptical ImagingBenzopyransFluorescent DyesXanthenesfluorescent imagingnear-infrared I/IIrhodaminetheranosticxanthene

Identifiers

PMID37114796
PMCPMC10288261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.