Evidence map›Paper›PMID 37114203›Full record

ArticleIJID regions2023

Burden of

Elias Alehegn, Alganesh Gebreyohanns, Bereket Berhane, Jayne Wright, Mengistu Fantahun, Michael Hailu, Bedo Buta, Melkayehu Kassa, Tsedale Woldu, Natnael Dejene and 5 more

Open access · goldAbstract read
In one paragraph

Article in IJID regions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Elias AlehegnSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Alganesh GebreyohannsSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Bereket BerhaneSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Jayne WrightJayne Wright Ltd, Pathology Consultancy, UK.
Mengistu FantahunSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Michael HailuEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Bedo ButaEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Melkayehu KassaSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Tsedale WolduSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Natnael DejeneSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Nuhamen ZenaSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Tewodros TesfayeRas Desta Damtew Memorial Hospital, Addis Ababa, Ethiopia.
Azeb GezahegnRas Desta Damtew Memorial Hospital, Addis Ababa, Ethiopia.
Tilahun GetinetAddis Ababa City Administration, Farmers and Urban Agriculture Development Commission, Addis Ababa, Ethiopia.
Addisu GizeSt Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
St. Paul's Hospital Millennium Medical College · ETAddis Ababa City Administration Health Bureau · ETEthiopian Public Health Institute · ETLMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Extra pulmonary tuberculosis (EPTB) accounts for a significant proportion of tuberculosis (TB), a devastating disease of public health concern. The complexity of the cases, the involvement of many organs, resource constraints, and concerns regarding drug resistance make disease diagnosis and treatment difficult. This study aimed to determine the burden of tuberculosis and associated factors among presumptive EPTB patients in selected hospitals in Addis Ababa. Material and methods: A cross-sectional study was conducted from February to August 2022 in selected public hospitals in Addis Ababa. Those who attended the hospitals and were presumptively diagnosed as EPTB patient were included in the study. Sociodemographic and clinical data were collected using a semistructured questionnaire. The GeneXpert MTB/RIF assay, Mycobacterium Growth Indicator Tube (MGIT) culture, and solid culture using Löwenstein-Jensen (LJ) medium were used. The data were entered and analyzed using SPSS version 23, and a Results: From a total of 308 participants enrolled in this study, the measured burdens of extrapulmonary tuberculosis using the Xpert MTB/RIF assay, liquid culture, and solid culture were 54 (17.5%), 45 (14.6%), and 39 (12.7%), respectively. In this study, sex, contact history with known TB cases, having a purulent type of aspirate, and being HIV positive had statistically significant associations with EPTB. Conclusions: The burden of extrapulmonary tuberculosis among presumptive extrapulmonary tuberculosis cases was found to be significant. Sex, contact history with a known TB case, having apurulent type of aspirate, and being HIV positive were found to be associated with extrapulmonary tuberculosis infection. Strict adherence to the national tuberculosis diagnosis and treatment guidelines is important, while the true burden of the disease should be ascertained using standard diagnostic tests for better prevention and control interventions.

Indexed as

Associated factorsExtra pulmonary tuberculosisGeneXpertMycobacterial culture

Identifiers

PMID37114203
PMCPMC10127111
OpenAlexW4353079153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.