Lateral ventricle chordoid meningioma presenting with inflammatory syndrome in an adult male: A case report.

Chordoid meningioma (CM) is a rare type of intracranial tumor. Intraventricular CM presenting with inflammatory syndrome is also rare. Meningioma is uncommonly accompanied by fever. The present case report documents a 28-year-old male who was admitted to the Affiliated Taian City Central Hospital of Qingdao University (Taian, China) with a 7-day history of unexplained fever and a 3-day history of progressive headache, which was accompanied with blurred vision in the right eye. Laboratory findings revealed an inflammatory condition with increased C-reactive protein levels, elevated erythrocyte sedimentation rate and moderate leukocytosis. MRI also revealed a lesion located in the right lateral ventricle. Subsequently, the tumor was excised through the right transtrigone lateral ventricle route and the tumor was then completely removed. H&E staining revealed characteristic cords of meningeal epithelial cells embedded in a prominent myxoid background, with numerous lymphocytes and plasma cells surrounding the tumor. Immunohistochemical analysis indicated focal positive staining for epithelial membrane antigen and S100, and negative staining for glial fibrillary acidic protein. Following pathological examination, the tumor was identified to be a CM. During the early postoperative course, the clinical symptoms disappeared and the hematological values returned to normal. No evidence of tumor recurrence was observed after 24 months of follow-up. To the best of our knowledge, the present study was the second to report the case of an adult patient with lateral ventricle CM presenting with inflammatory syndrome and it was the first case in an adult male.