Evidence map›Paper›PMID 37114056›Full record

ArticleFrontiers in immunology2023

Effects of dietary tryptophan on the antioxidant capacity and immune response associated with TOR and TLRs/MyD88/NF-κB signaling pathways in northern snakehead,

Xin Zhang, Anran Wang, Enhui Chang, Bei Han, Jie Xu, Yu Fu, Xiaojing Dong, Shuyan Miao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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  7. Probiotic Roles ofAnimals : an open access journal from MDPI · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xin ZhangAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Anran WangAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Enhui ChangAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Bei HanAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Jie XuAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yu FuAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Xiaojing DongAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Shuyan MiaoAquaculture Nutrition and Feed Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Dietary tryptophan (Trp) has been shown to influence fish feed intake, growth, immunity and inflammatory responses. The purpose of this study was to investigate the effect and mechanism of Trp on immune system of juvenile northern snakehead ( Methods: A total of 540 fish (10.21 ± 0.11 g) were fed six experimental diets containing graded levels of Trp at 1.9, 3.0, 3.9, 4.8, 5.9 and 6.8 g/kg diet for 70 days, respectively. Results and Discussion: The results showed that supplementation of 1.9-4.8 g/kg Trp in diets had no effect on the hepatosomatic index (HSI) and renal index (RI), while dietary 3.9 and 4.8 g/kg Trp significantly increased spleen index (SI) of fish. Dietary 3.9, 4.8, 5.9 and 6.8 g/kg Trp enhanced the total hemocyte count (THC), the activities of total antioxidant capacity (T-AOC) and superoxide dismutase (SOD). Malondinaldehyde (MDA) levels in the blood were significantly decreased by consuming 3.9 and 4.8 g/kg Trp. Fish fed with 3.0 and 3.9 g/kg Trp diets up-regulated interleukin 6 (

Indexed as

AntioxidantsCarpsAdaptor Proteins, Signal TransducingAnimalsDietDietary SupplementsFishesImmunityInterleukin-6Myeloid Differentiation Factor 88NF-kappa BPyridazinesRNA, MessengerSignal TransductionToll-Like ReceptorsTryptophanAdaptor Proteins, Signal TransducingAntioxidantsInterleukin-6minaprineMyeloid Differentiation Factor 88NF-kappa BPyridazinesRNA, MessengerToll-Like ReceptorsTryptophanTumor Necrosis Factor-alphaantioxidant capacitynorthern snakehead Channa argusTLRs/MyD88/NF-κB signaling pathwayTOR signaling pathwaytryptophan

Identifiers

PMID37114056
PMCPMC10128191
OpenAlexW4364376632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.