Evidence map›Paper›PMID 37114052›Full record

ArticleFrontiers in immunology2023

CD90 is not constitutively expressed in functional innate lymphoid cells.

Jan-Hendrik Schroeder, Gordon Beattie, Jonathan W Lo, Tomasz Zabinski, Nick Powell, Joana F Neves, Richard G Jenner, Graham M Lord

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jan-Hendrik SchroederSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Gordon BeattieCancer Research UK (CRUK) City of London Centre Single Cell Genomics Facility, University College London Cancer Institute, University College London (UCL), London, United Kingdom.
Jonathan W LoSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Tomasz ZabinskiSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Nick PowellDivision of Digestive Diseases, Faculty of Medicine, Imperial College London, London, United Kingdom.
Joana F NevesSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Richard G JennerUniversity College London (UCL) Cancer Institute, University College London, London, United Kingdom.
Graham M LordSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
King's College London · GBImperial College London · GBLondon Cancer · GBUniversity College London · GB

Funding

Cancer Research UK C7893/A26233Medical Research Council MR/K002996/1Medical Research Council MR/M003493/1Medical Research Council MR/R024812/1Wellcome Trust
6 · The paper itself

Abstract

Huge progress has been made in understanding the biology of innate lymphoid cells (ILC) by adopting several well-known concepts in T cell biology. As such, flow cytometry gating strategies and markers, such as CD90, have been applied to indentify ILC. Here, we report that most non-NK intestinal ILC have a high expression of CD90 as expected, but surprisingly a sub-population of cells exhibit low or even no expression of this marker. CD90-negative and CD90-low CD127

Indexed as

ColitisImmunity, InnateCytokinesDysbiosisHumansLymphocytesThy-1 AntigensCytokinesThy-1 AntigensCD90DSS-colitisfecal microbial transplant (FMT)innate lymphoid cell (ILC)intestine

Identifiers

PMID37114052
PMCPMC10126679
OpenAlexW4364367857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.