Evidence map›Paper›PMID 37114014›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Determinants of informal care time, distress, depression, and quality of life in care partners along the trajectory of Alzheimer's disease.

Arenda Mank, Ingrid S van Maurik, Judith J M Rijnhart, Hanneke F M Rhodius-Meester, Leonie N C Visser, Afina W Lemstra, Sietske A M Sikkes, Charlotte E Teunissen, Elsmarieke M van Giessen, Johannes Berkhof and 1 more

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Arenda MankAlzheimer Center Amsterdam, Department of Neurology Vrije Universiteit Amsterdam Amsterdam UMC VUmc Amsterdam the Netherlands.
Ingrid S van MaurikAlzheimer Center Amsterdam, Department of Neurology Vrije Universiteit Amsterdam Amsterdam UMC VUmc Amsterdam the Netherlands.
Judith J M RijnhartCollege of Public Health University of South Florida Tampa Florida USA.
Hanneke F M Rhodius-MeesterAlzheimer Center Amsterdam, Department of Neurology Vrije Universiteit Amsterdam Amsterdam UMC VUmc Amsterdam the Netherlands.
Leonie N C VisserDepartment of Medical Psychology Amsterdam UMC, AMC University of Amsterdam Amsterdam the Netherlands.
Afina W LemstraAlzheimer Center Amsterdam, Department of Neurology Vrije Universiteit Amsterdam Amsterdam UMC VUmc Amsterdam the Netherlands.
Sietske A M SikkesAlzheimer Center Amsterdam, Department of Neurology Vrije Universiteit Amsterdam Amsterdam UMC VUmc Amsterdam the Netherlands.
Charlotte E TeunissenAmsterdam Neuroscience Neurodegeneration Amsterdam the Netherlands.
Elsmarieke M van GiessenDepartment of Radiology & Nuclear Medicine Vrije Universiteit Amsterdam Amsterdam UMC, VUmc Amsterdam the Netherlands.
Johannes BerkhofAmsterdam UMC Vrije Universiteit Amsterdam Department of Epidemiology and Data Science Amsterdam Public Health Institute Amsterdam the Netherlands.
Wiesje M van der FlierAlzheimer Center Amsterdam, Department of Neurology Vrije Universiteit Amsterdam Amsterdam UMC VUmc Amsterdam the Netherlands.
Amsterdam University Medical Centers · NLVrije Universiteit Amsterdam · NLAmsterdam Neuroscience · NLUniversity of Amsterdam · NLUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We evaluated determinants associated with care partner outcomes along the Alzheimer's disease (AD) stages. Methods: We included Results: More behavioral symptoms and functional impairment in patients were associated with more informal care time and depressive symptoms in care partners. More behavioral symptoms were related with more caregiver distress. Spouse care partners spent more time on informal care and QoL was lower in female care partners. Behavioral problems and subtle functional impairment of the patient predisposed for worse care partner outcomes already in the pre-dementia stages. Discussion: Both patient and care partner determinants contribute to the care partner outcomes, already in early disease stages. This study provides red flags for high care partner burden.

Indexed as

Alzheimer's diseasecaregiverdementiadepressioninformal care timemild cognitive impairmentquality of lifesubjective cognitive decline

Identifiers

PMID37114014
PMCPMC10126754
OpenAlexW4366992601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.