Evidence map›Paper›PMID 37113975›Full record

ArticleAnnals of medicine and surgery (2012)2023

Clinicopathological correlation of aspartate aminotransferase-to-platelet ratio (APRI) and aspartate aminotransferase-to-alanine aminotransferase ratio (AAR) with survival in esophageal carcinoma patients: a retrospective cohort analysis of 951 patients.

Muhammad Talha Zafar, Beenish Fatima Zia, Saleha Rashid Khalid, Jharna Bai, Zahid Ali Memon, Zaka Ullah Jan, Sarosh Khan Jadoon, Noman Ahmed Khan, Diksha Kajal, Farukh Ali and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Muhammad Talha ZafarDHQ Hospital, Jauharabad.
Beenish Fatima ZiaFMH College of Medicine and Dentistry, Lahore, Punjab.
Saleha Rashid KhalidFMH College of Medicine and Dentistry, Lahore, Punjab.
Jharna BaiShaheed Mohtarma Benazir Bhutto Medical University (SMBBMU), Larkana, Sindh.ORCID 0000-0002-2819-5335
Zahid Ali MemonCivil Hospital.
Zaka Ullah JanKhyber Teaching Hospital, Peshawar.
Sarosh Khan JadoonCMH Muzaffarabad, Azad Kashmir, Pakistan.
Noman Ahmed KhanKhyber Teaching Hospital, Peshawar.
Diksha KajalGhulam Muhammad Mahar Medical College, Sukkur.
Farukh AliJinnah Medical and Dental College.ORCID 0000-0002-8704-8124
Tooba Ahmed KirmaniDow University Hospital-Ojha Campus, Dow University of Health Sciences, Karachi.
Muhammad Sohaib AsgharDow University Hospital-Ojha Campus, Dow University of Health Sciences, Karachi.
CMH Lahore Medical College and Institute of Dentistry · PKDow University of Health Sciences · PKKhyber Teaching Hospital · PKCivil Hospital Karachi · PKFarooq Hospital · PKJinnah Medical & Dental College · PKShaheed Mohtarma Benazir Bhutto Medical University · PKSukkur IBA University · PKUniversity of Azad Jammu and Kashmir · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer is the eighth most prevalent cancer globally. Previously, several biomarkers have been used to predict the prognosis, although with variable reliability. Interestingly, it is noted that changes in liver function tests levels before and after neoadjuvant treatment are predictive in terms of cancer recurrence. Objectives: The objectives of the current study were to associate novel markers, including aspartate aminotransferase-to-platelet ratio (APRI) and aspartate aminotransferase-to-alanine aminotransferase ratio (AAR) with survival in esophageal malignancy. Materials and Methods: A retrospective study in a tertiary care hospital (single-center) included 951 patients having diagnosed esophageal carcinoma of any age group. Results: The median (interquartile range) age of study participants were 50 (38-60) years, including 43% males and 57% female patients, while the median (interquartile range) levels of AAR and APRI were 0.97 (0.81-1.25) and 0.19 (0.13-0.29), respectively. AAR was found to be higher in dysphagia for solids only and dysphagia for both liquids and solids rather than liquids only ( Conclusion: This study correlated clinical and pathological features of esophageal malignancy with noninvasive markers of hepatic function.

Indexed as

esophagushistopathologymalignancymortalitysurvival

Identifiers

PMID37113975
PMCPMC10129076
OpenAlexW4361287295

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.