Evidence map›Paper›PMID 37113910›Full record

ArticleAnnals of medicine and surgery (2012)2023

Levels of SARS-COV-2 anti-spike protein receptor-binding domain (S-RBD) IgG in Indonesian-vaccinated healthcare workers: experimental research.

Betty A Tambunan, I Dewa G Ugrasena, Jusak Nugraha, Munawaroh Fitriah, Cynthia A Permatasari, Emmanuel J Moses, Narazah M Yusoff, Aryati

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Betty A TambunanDoctoral Program of Medical Science, Faculty of Medicine.ORCID 0000-0002-3214-993X
I Dewa G UgrasenaDepartment of Pediatrics, Faculty of Medicine, Universitas Airlangga, Surabaya.
Jusak NugrahaDepartment of Clinical Pathology, Faculty of Medicine.
Munawaroh FitriahDepartment of Clinical Pathology, Faculty of Medicine.
Cynthia A PermatasariDepartment of Clinical Pathology, Faculty of Medicine.
Emmanuel J MosesMedical and Dental Institute, Universiti Sains Malaysia (USM), Kepala Batas, Penang, Malaysia.
Narazah M YusoffDepartment of Clinical Pathology, Faculty of Medicine.
AryatiDepartment of Clinical Pathology, Faculty of Medicine.ORCID 0000-0002-9383-6354
Universitas Dr. Soetomo · IDAirlangga University · IDUniversiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies evaluating the levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-spike protein receptor-binding domain (S-RBD) immunoglobulin G (IgG) antibodies in vaccinated healthcare workers in Indonesia are limited. Objectives: Evaluating time-dependent levels of anti-IgG S-RBD antibodies and monitoring the response of healthcare workers in a tertiary hospital in Indonesia after vaccination. Materials and methods: This prospective cohort observational study was conducted from January to December 2021. A total of 50 healthcare workers participated in the study. Blood samples were collected at five time points. Antibody levels were measured using a CL 1000i analyzer (Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, China). Antibody levels between groups were analyzed using the Wilcoxon signed-rank test with Results: The median levels of SARS-CoV-2 anti-S-RBD IgG antibody on days 14, 28, 90, and 180 were significantly higher than the levels on day 0 ( Conclusion: SARS-CoV-2 anti-S-RBD IgG antibody levels increased significantly until day 14 after the second dose; the levels decreased gradually after day 28. Ten participants (20%) were infected with SARS-CoV-2, with mild symptoms.

Indexed as

CoronaVac vaccinehealthcare workersinfectious diseaseSARS-CoV-2 anti-spike protein RBD IgG

Identifiers

PMID37113910
PMCPMC10129122
OpenAlexW4362582049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.