Evidence map›Paper›PMID 37113903›Full record

ArticleAnnals of medicine and surgery (2012)2023

Wallerian degeneration in the brain after organophosphorus poisoning: a case report.

Bikram P Gajurel, Subarna Giri, Navin Poudel, Sanjeev Kharel, Ragesh Karn, Reema Rajbhandari, Rajeev Ojha, Niraj Gautam, Aashish Shrestha

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In one paragraph

Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Bikram P GajurelDepartment of Neurology.ORCID 0000-0002-9995-0705
Subarna GiriMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.ORCID 0000-0001-8876-5232
Navin PoudelMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.ORCID 0000-0001-8597-1495
Sanjeev KharelMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.ORCID 0000-0001-9591-3168
Ragesh KarnDepartment of Neurology.ORCID 0000-0002-6926-4878
Reema RajbhandariDepartment of Neurology.ORCID 0000-0002-8728-3896
Rajeev OjhaDepartment of Neurology.ORCID 0000-0001-7680-7036
Niraj GautamDepartment of Neurology.ORCID 0000-0002-1675-0493
Aashish ShresthaDepartment of Neurology.
Tribhuvan University Teaching Hospital · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The type, quantity, and potency of the organophosphorus compound (OPC) taken determine the symptoms of OPC poisoning as well as their severity. The exact etiology for organophosphorus (OP) poisoning delay neuropathy regulating Wallerian degeneration is still unknown. Case Presentation: We report here a rare case of a 25-year-old lady with Wallerian degeneration in the brain found in an MRI in a patient after OPC ingestion. MRI of the brain, in our case, shows Wallerian degeneration of the corona radiata, internal capsule, and midbrain. Clinical Discussion: Some OPCs can lead to OP-induced delayed neuropathy, a form of delayed neurotoxicity in humans (OPIDN). The distal axonopathy's (in OPIDN) morphological pattern resembles Wallerian degeneration, which happens Conclusion: Central nervous system involvement after OP poisoning is rare, and MRI of the brain and spinal cord can document evidence of Wallerian degeneration after OP poisoning.

Indexed as

case reportCNS involvementOP poisoning delay neuropathyWallerian degeneration

Identifiers

PMID37113903
PMCPMC10129287
OpenAlexW4362581723

What OpenQuestion holds

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LicenceCC BY-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.