Evidence map›Paper›PMID 37113726›Full record

ArticleEcancermedicalscience2023

Pattern and predictors of cervical epithelial cell abnormalities among unscreened and under-screened women in Lagos, Nigeria: a cross-sectional study.

Adeyemi Adebola Okunowo, Aloy Okechukwu Ugwu, Azeezat Oluwafunmilayo Ajose, Jubril Oladapo Kuku, Bolanle Olajumoke Okunowo, Nneoma Kwemtochukwu Ani-Ugwu, Benedetto Oluwaseun Osunwusi, Muisi Alli Adenekan, Adaiah Priscillia Soibi-Harry, Sunusi Rimi Garba

Open access · goldAbstract read
In one paragraph

Article in Ecancermedicalscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Adeyemi Adebola OkunowoDepartment of Obstetrics & Gynaecology, College of Medicine, University of Lagos (CMUL), Idi-Araba 102215, Lagos, Nigeria.
Aloy Okechukwu UgwuDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Idi-Araba 102215, Lagos, Nigeria.
Azeezat Oluwafunmilayo AjoseDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Idi-Araba 102215, Lagos, Nigeria.
Jubril Oladapo KukuDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Idi-Araba 102215, Lagos, Nigeria.
Bolanle Olajumoke OkunowoDepartment of Internal Medicine, Lagos State University Teaching Hospital (LASUTH), Ikeja 101233, Lagos, Nigeria.
Nneoma Kwemtochukwu Ani-UgwuDepartment of Internal Medicine, Lagos University Teaching Hospital (LUTH), Idi-Araba 102215, Lagos, Nigeria.
Benedetto Oluwaseun OsunwusiDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Idi-Araba 102215, Lagos, Nigeria.
Muisi Alli AdenekanLagos Island Maternity Hospital, 10 Campbell street, Lagos Island, 102273, Lagos, Nigeria.
Adaiah Priscillia Soibi-HarryDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Idi-Araba 102215, Lagos, Nigeria.
Sunusi Rimi GarbaDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Idi-Araba 102215, Lagos, Nigeria.
Lagos University Teaching Hospital · NGLagos State University Teaching Hospital · NGTwitter (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women who had never undergone cervical screening (CS) or who have infrequent CS are at increased risk of having cervical epithelial cell abnormalities (CECA) that may lead to cervical cancer (CCa). Our study determined the pattern and factors that predict the occurrence of CECA among unscreened and under-screened women in Lagos, Nigeria. This was an analytical cross-sectional study among 256 consenting sexually active women between 21 and 65 years who attended a community CS programme in Surulere, Lagos, Nigeria, in June 2019. Information on socio-demographic, reproductive, sexual, behavioural and clinical characteristics were collected and a Pap smear test was done. Women with abnormal cervical cytology were followed up and given appropriate treatment. Data analysis was done using Statistical Package for Social Sciences version 23. Descriptive statistics were computed using frequencies and association was tested using odd ratio. The participants' mean age was 42.7 ± 10.3 years, majority were married (79.9%) and were human immune deficiency syndrome (HIV) negative (63.1%). The prevalence of CECA was 9.8%. Atypical squamous cell of undetermined significance and atypical squamous cell cannot exclude high-grade squamous intraepithelial lesion were the most common CECA with prevalence rates of 7.4% and 2.0%, respectively. Having a partner with multiple sexual partners (adjusted odd ratio (AOR) = 19.23), being HIV positive (AOR = 25.61), giving birth for the first time before the age of 26 years (AOR = 5.55) and presence of a combination of either abnormal vaginal discharge, contact bleeding or an unhealthy cervix on clinical examination (AOR = 13.65) independently predicted the occurrence of CECA. There is a need to prioritise CS for women with these risk factors to prevent CCa and reduce the burden of the disease in our environment.

Indexed as

cervical cancercervical epithelial cell abnormalitycervical screeningNigeriapredictorsunder-screened womenunscreened women

Identifiers

PMID37113726
PMCPMC10129382
OpenAlexW4319296038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.