Evidence map›Paper›PMID 37113475›Full record

ArticleSaudi journal of biological sciences2023

Chemical characterization and toxicity evaluation of fungal pigments for potential application in food, phamarceutical and agricultural industries.

Tumisi Beiri Jeremiah Molelekoa, Wilma Augustyn, Thierry Regnier, Laura Suzanne da Silva

Abstract read
In one paragraph

Article in Saudi journal of biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Pigment Production byMicroorganisms · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tumisi Beiri Jeremiah MolelekoaDepartment of Biotechnology and Food Technology, Arcadia Campus, Tshwane University of Technology, Pretoria, Private Bag X680, Pretoria 0001, South Africa.
Wilma AugustynDepartment of Chemistry, Arcadia Campus, Tshwane University of Technology, Pretoria, Private Bag X680, Pretoria 0001, South Africa.
Thierry RegnierDepartment of Biotechnology and Food Technology, Arcadia Campus, Tshwane University of Technology, Pretoria, Private Bag X680, Pretoria 0001, South Africa.
Laura Suzanne da SilvaDepartment of Biotechnology and Food Technology, Arcadia Campus, Tshwane University of Technology, Pretoria, Private Bag X680, Pretoria 0001, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Concerns associated with the use of synthetic colourants backs the demand for natural colourants. Thus, the current study aimed at characterizing crude fungal pigments produced by Penicillium multicolour, P. canescens, Talaromyces verruculosus, Fusarium solani and P. herquie. This included their antioxidant and antimicrobial properties together with acute toxicity evaluation on zebrafish embryos. The identification of pigment compounds was achieved through MS and IR data. The study demonstrated a substantial radical scavenging activity of extracts ranging from 65.49 to 74.46%, close to that of ascorbic acid (89.21%). Penicillium canescens and F. solani exhibited a strong antimicrobial activity against Escherichia coli and Enterococcus aerogenes and Salmonella typhi, Staphylococcus aureus and Bacillus cereus at MIC values ranging from 1.5 to 2.5 mg/mL. However, some levels of toxicity were observed for all extracts at a concentration range of 3-5 mg/mL. Pigment by P. multicolour, T. verruculosus and F. solani were tentatively identified through IR and MS data as sclerotiorin (yellow), rubropunctamine (red) and bostrycoidin (red). In conclusion, the study demonstrates a market potential of filamentous fungi pigments due to their antioxidant, antimicrobial activities, and prominent colours. Although there are some toxicity concerns, further tests must be done using molecular docking, albino mice and cell linings.

Indexed as

AntimicrobialAntioxidantFish Embryo ToxicityFITRFungal PigmentsUPLC

Identifiers

PMID37113475
PMCPMC10127131

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.