ArticleCureus2023
Intraoperative Assessment of Margin Accuracy in Early Oral Squamous Cell Carcinoma (cT1, T2, N0): Clinical Versus Frozen Section Analysis.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Assessment and interpretation of the status of surgical margins following resective surgery for head and neck squamous cancer: a narrative review.World journal of surgical oncology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background The incidence of oral cavity cancer is increasing. During oral carcinoma surgery, to achieve a tumor-free margin, intraoperative margin assessment includes two primary methods, namely, clinical examination and frozen section analysis. With extensive preoperative imaging investigations and intraoperative clinical margin assessment, the need for further cost and resource-intensive frozen section analysis has recently come under question. This study aimed to assess whether frozen section analysis can be safely omitted in most cases of early oral squamous cell carcinoma surgeries for cost-effectiveness. Methodology A hospital-based, observational study including 30 admitted cases of early oral squamous cell carcinoma was conducted at the Department of General Surgery, Pradyumna Bal Memorial Hospital, Bhubaneswar. All consecutive confirmed cases of early oral squamous cell carcinoma of all age groups and both genders after considering the inclusion and exclusion criteria were involved in the study. A comparative assessment of the free margins after tumor excision was done by the surgeon followed by frozen section analysis. Results The mean age was 53.03 ± 13.72 years, with a male-to-female ratio of 6.5:1. Carcinoma of the lower alveolus with gingivobuccal sulcus was the most common presentation of the study (33.33%). In our study, clinically assessed margins had a sensitivity of 75.39%, a specificity of 94.43%, and an accuracy of 92.77%. Frozen section assessed margins had a sensitivity of 66.5%, a specificity of 96.94%, and an accuracy of 92.77%. Conclusions Based on the accuracy of clinically assessed and frozen section assessed margins, this study concluded that surgically resected/excised specimen by the surgeon plays a vital role in assessing the adequacy of resected/excised margins in early oral squamous cell carcinoma (cT1, T2, N0) cases, which can possibly replace the costly frozen section analysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.