Evidence map›Paper›PMID 37113306›Full record

ArticlePlastic and reconstructive surgery. Global open2023

Closed Incision Negative Pressure Therapy in Oncoplastic Breast Surgery: A Comparison of Outcomes.

Carly M Wareham, Manish M Karamchandani, Gabriel De La Cruz Ku, Kerry Gaffney, Yurie Sekigami, Sarah M Persing, Christopher Homsy, Salvatore Nardello, Abhishek Chatterjee

Registry-linked trialAbstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07607366 (Is Negative Pressure Wound Therapy Associated With a Decreased Risk of Postoperative Seroma in Breast Cancer Patients Who Have Undergone Mastectomy?), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07607366 narecruitingnot on this mapstarted 2025, after this paper: background citation

Is Negative Pressure Wound Therapy Associated With a Decreased Risk of Postoperative Seroma in Breast Cancer Patients Who Have Undergone Mastectomy?

TypeinterventionalSponsorDalarna County Council, SwedenRan2025 to 2027Enrolled76ConditionsBreast Cancer - FemaleArmsPICO negative pressure wound therapy by Smith and Nephew
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carly M WarehamDepartment of Surgery, Tufts Medical Center, Boston, Mass.
Manish M KaramchandaniDepartment of Surgery, Tufts Medical Center, Boston, Mass.
Gabriel De La Cruz KuUniversity of Massachusetts Medical School, Worcester, Mass.
Kerry GaffneyDepartment of Surgery, Tufts Medical Center, Boston, Mass.
Yurie SekigamiDepartment of Surgery, Tufts Medical Center, Boston, Mass.
Sarah M PersingDivision of Plastic and Reconstructive Surgery, Department of Surgery, Tufts Medical Center, Boston, Mass.
Christopher HomsyDivision of Plastic and Reconstructive Surgery, Department of Surgery, Tufts Medical Center, Boston, Mass.
Salvatore NardelloDivision of Surgical Oncology and Breast Surgery, Department of Surgery, Tufts Medical Center, Boston, Mass.
Abhishek ChatterjeeDivision of Plastic and Reconstructive Surgery, Department of Surgery, Tufts Medical Center, Boston, Mass.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aim to discern the impact of closed incision negative pressure therapy (ciNPT) on wound healing in the oncoplastic breast surgery population. Methods: A retrospective analysis was conducted on patients who underwent oncoplastic breast surgery with and without ciNPT in a single health system over 6 years. Oncoplastic breast surgery was defined as breast conservation surgery involving partial mastectomy with immediate volume displacement or replacement techniques. Primary outcomes were rates of clinically significant complications requiring either medical or operative intervention, including seroma, hematoma, fat necrosis, wound dehiscence, and infection. Secondary outcomes were rates of minor complications. Results: ciNPT was used in 75 patients; standard postsurgical dressing was used in 142 patients. Mean age ( Conclusions: The use of ciNPT reduces the overall rate of clinically relevant postoperative complications, including wound dehiscence. The ciNPT cohort had higher rates of macromastia symptoms, BMI, and ASA, all of which put them at increased risk for complications. Therefore, ciNPT should be considered in the oncoplastic population, especially in those patients with increased risk for postoperative complications.

Identifiers

PMID37113306
PMCPMC10129093

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.