Evidence map›Paper›PMID 37113225›Full record

ArticleFrontiers in microbiology2023

Genomic, transcriptomic, and metabolic characterization of 2-Phenylethanol-resistant

Can Holyavkin, Burcu Turanlı-Yıldız, Ülkü Yılmaz, Ceren Alkım, Mevlüt Arslan, Alican Topaloğlu, Halil İbrahim Kısakesen, Gustavo de Billerbeck, Jean Marie François, Z Petek Çakar

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

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  3. EngineeringFrontiers in microbiology · 2026
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  15. FromJournal of fungi (Basel, Switzerland) · 2023
    Review
  16. Article
  17. Tyrosol induces multiple drug resistance in yeastFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Can HolyavkinDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Burcu Turanlı-YıldızDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Ülkü YılmazDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Ceren AlkımDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Mevlüt ArslanDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Alican TopaloğluDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Halil İbrahim KısakesenDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Gustavo de BillerbeckINSA, UPS, INP, Université de Toulouse, Toulouse, France.
Jean Marie FrançoisToulouse Biotechnology Institute (TBI), CNRS, INRA, INSA, Université de Toulouse, Toulouse, France.
Z Petek ÇakarDepartment of Molecular Biology & Genetics, Faculty of Science & Letters, Istanbul Technical University, Istanbul, Turkey.
Istanbul Technical University · TRCentre National de la Recherche Scientifique · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2-Phenylethanol is an aromatic compound commonly used in the food, cosmetic, and pharmaceutical industries. Due to increasing demand for natural products by consumers, the production of this flavor by microbial fermentation is gaining interest, as a sustainable alternative to chemical synthesis or expensive plant extraction, both processes relying on the use of fossil resources. However, the drawback of the fermentation process is the high toxicity of 2-phenylethanol to the producing microorganism. The aim of this study was to obtain a 2-phenylethanol-resistant

Indexed as

2-phenylethanoladaptive laboratory evolutionenvironmental stress responseevolutionary engineeringgenomic analysisSaccharomyces cerevisiaestress resistancetranscriptomic analysis

Identifiers

PMID37113225
PMCPMC10127108
OpenAlexW4364379668

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.