ArticleFrontiers in cellular and infection microbiology2023
Correlation between caries activity and salivary microbiota in preschool children.
Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Oral microbiome dynamics in head and neck cancer patients undergoing oral healthcare: implications for prognosis and early diagnosis.BMC microbiology · 2025Trial
- Salivary microbiome and metabolome profiles associated with dental caries in Tibetan children from high-altitude regions.Odontology · 2026Article
- Modulating Oral Microbiota to Prevent Dental Caries: A Microbial Ecology Approach.Dentistry journal · 2026Review
- Interindividual differences in acidogenic potential of the salivary microbiome after mouthwash exposure.BMC microbiology · 2026Article
- Age-Related Trends of Caries Experience Among Preschool Children in Shenzhen, China: A Cross-Sectional Study.Dentistry journal · 2026Article
- Biological Validation of the PSC-MCAT: Analyzing Dental Plaque Microbiota Across Caries Risk Levels in Preschoolers.International dental journal · 2026Article
- Mapping the oral microbiome in children with oral diseases using next-generation sequencing: a systematic review.Journal of oral microbiology · 2026Review
- Caries Activity and Its Associated Factors Among Primary Caregivers of Preschool Children.International journal of dentistry · 2026Article
- Ensemble learning for microbiome-based caries diagnosis: multi-group modeling and biological interpretation from salivary and plaque metagenomic data.BMC oral health · 2025Article
- Investigation of dental health and salivary microbiota characteristics of children with visual impairment in Guangzhou, China.BMC oral health · 2025Article
- Association between early childhood caries and anthropometric growth and nutritional status in preschool children: a cross-sectional study.Frontiers in pediatrics · 2025Article
- Article
- Relationship of dietary nutrients with early childhood caries and caries activity among children aged 3-5 years-a cross-sectional study.BMC pediatrics · 2024Article
- Effects of personalized oral hygiene management on oral health status of pregnant women.World journal of clinical cases · 2024Article
- Combined effect of dietary calcium consumption and physical activity on dental caries in children and adolescents: a study of the NHANES database.BMC oral health · 2024Article
- Oral microbiota analyses of paediatric Saudi population reveals signatures of dental caries.BMC oral health · 2023Article
- Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early childhood caries (ECC) is the most common chronic infectious oral disease in preschool children worldwide. It is closely related to the caries activity (CA) of children. However, the distribution characteristics of oral saliva microbiomes in children with different CA are largely underexplored. The aim of this study was to investigate the microbial community in saliva of preschool children with different CA and caries status, and to analyze the difference of microbial community in saliva of children with different CA and its correlation with ECC. Subjects were divided into 3 groups based on the Cariostat caries activity test: Group H, high CA (n=30); Group M, medium CA (n = 30); Group L, low CA (n=30). Questionnaire survey was used to explore the related influencing factors of CA. According to the caries status (on the basis of decayed mising filled teeth), these subjects were divided into caries-free group (dmft=0, n=19), caries-low group (0 < dmft ≤ 4, n=27) and caries-high group (dmft > 4, n=44). Microbial profiles of oral saliva were analyzed using 16S rRNA gene sequencing. There were significant differences in the microbial structure (
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