Evidence map›Paper›PMID 37113066›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

Insulin resistance and body mass index are associated with TSPO PET in cognitively unimpaired elderly.

Laura L Ekblad, Jouni Tuisku, Mikko Koivumäki, Semi Helin, Juha O Rinne, Anniina Snellman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Diabetes-Associated Cognitive Impairment: Pathophysiology and Emerging Therapies.Annals of clinical and translational neurology · 2026
    Review
  2. Review
  3. A [Journal of neuroinflammation · 2025
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laura L EkbladTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.ORCID 0000-0002-5863-8088
Jouni TuiskuTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Mikko KoivumäkiTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Semi HelinTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Juha O RinneTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Anniina SnellmanTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
University of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic risk factors are associated with peripheral low-grade inflammation and an increased risk for dementia. We evaluated if metabolic risk factors i.e. insulin resistance, body mass index (BMI), serum cholesterol values, or high sensitivity C-reactive protein associate with central inflammation or beta-amyloid (Aβ) accumulation in the brain, and if these associations are modulated by

Indexed as

Alzheimer DiseaseBody Mass IndexInsulin ResistanceReceptors, GABAAgedApolipoproteins ECholesterol, HDLCholesterol, LDLC-Reactive ProteinCross-Sectional StudiesDementiaFemaleHumansInflammationMalePositron-Emission TomographyApoE protein, humanApolipoproteins ECholesterol, HDLCholesterol, LDLC-Reactive ProteinReceptors, GABATSPO protein, humanAlzheimerAPOE genotypemetabolic risk factorPK11195TSPO

Identifiers

PMID37113066
PMCPMC10414007
OpenAlexW4367299942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.