Evidence map›Paper›PMID 37113027›Full record

ReviewEuropean journal of ophthalmology2024

New insights in the multimodal imaging of retinitis pigmentosa.

Alessandro Berni, Alessandro Arrigo, Lorenzo Bianco, Alessio Antropoli, Andrea Saladino, Ahmad M Mansour, Manuel Vilela, Francesco Bandello, Maurizio Battaglia Parodi

Open access · hybridAbstract readReview
In one paragraph

Review in European journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Alessandro BerniDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-6412-1288
Alessandro ArrigoDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-4715-8414
Lorenzo BiancoDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-4023-5387
Alessio AntropoliDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0001-9630-0830
Andrea SaladinoDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ahmad M MansourDepartment of Ophthalmology, American University of Beirut, Beirut, Lebanon.ORCID 0000-0001-8430-2214
Manuel VilelaFederal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil.ORCID 0000-0002-3290-419X
Francesco BandelloDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-3238-9682
Maurizio Battaglia ParodiDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Vita-Salute San Raffaele University · ITAmerican University of Beirut · LBUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is a group of inherited rod-cone dystrophies, noted for a high genotypical and phenotypical heterogeneity.Traditionally, VA, visual field, and electroretinography have been used to assess RP progression. However, visual acuity and visual field tests are essentially subjective and, especially in the late stages of the disease, are unable to confidently reveal minor progression. Therefore, there is a need for novel examination modalities that rely on quantitative, structural measurements. In this regard, several non-invasive imaging techniques have been studied, including spectral-domain optical coherence tomography, optical coherence tomography angiography, and fundus autofluorescence. By correlating surrogate biomarkers with functional measurements of the disease, these techniques may be able to develop reliable outcome meters that can be used to gain a deeper understanding of the underlying causes of the disease and to assess the effectiveness of therapy even before an actual loss of vision occurs.In this review, we will summarize the recent imaging findings and biomarkers that have been identified in RP patients. Our goal is to provide information that can promptly aid in selecting patients for clinical trials and new gene therapies, monitoring the disease progression, and evaluating treatment outcomes.

Indexed as

Retinitis PigmentosaBiomarkersElectroretinographyHumansMultimodal ImagingRetinaTomography, Optical CoherenceVisual FieldsBiomarkersimagingOCTOCTAretinaRetinitis pigmentosa

Identifiers

PMID37113027
PMCPMC10898209
OpenAlexW4367318300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.