Evidence map›Paper›PMID 37112911›Full record

ArticleViruses2023

The SUMOylation of Human Cytomegalovirus Capsid Assembly Protein Precursor (UL80.5) Affects Its Interaction with Major Capsid Protein (UL86) and Viral Replication.

Zhigang Zhang, Sisi Xia, Zhigang Wang, Nina Yin, Jun Chen, Luyao Shao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhigang ZhangBasic Medical College, Hubei University of Chinese Medicine, Wuhan 430065, China.
Sisi XiaDepartment of Biological Engineering, Wuhan Polytechnic University, Wuhan 430023, China.
Zhigang WangBasic Medical College, Hubei University of Chinese Medicine, Wuhan 430065, China.
Nina YinBasic Medical College, Hubei University of Chinese Medicine, Wuhan 430065, China.
Jun ChenGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-2447-0544
Luyao ShaoBasic Medical College, Hubei University of Chinese Medicine, Wuhan 430065, China.
Hubei University of Chinese Medicine · CNJinan University · CNWuhan Polytechnic University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Cytomegalovirus Capsid Assembly Protein Precursor (pAP, UL80.5) plays a key role in capsid assembly by forming an internal protein scaffold with Major Capsid Protein (MCP, UL86) and other capsid subunits. In this study, we revealed UL80.5 as a novel SUMOylated viral protein. We confirmed that UL80.5 interacted with the SUMO E2 ligase UBC9 (58-93aa) and could be covalently modified by SUMO1/SUMO2/SUMO3 proteins.

Indexed as

CapsidCapsid ProteinsCytomegalovirusHumansLysineProtein PrecursorsSmall Ubiquitin-Related Modifier ProteinsSumoylationViral ProteinsVirus ReplicationCapsid ProteinsLysineProtein PrecursorsSmall Ubiquitin-Related Modifier ProteinsViral Proteinscapsid assemblyhuman cytomegalovirus (HCMV)SUMOylationUL80.5

Identifiers

PMID37112911
PMCPMC10145422
OpenAlexW4363677259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.