Evidence map›Paper›PMID 37112823›Full record

ArticleViruses2023

Orthopoxvirus Circulation in an Endemic Area in Brazil: Investigation of Infections in Small Mammals during an Absence of Outbreaks.

Iago J S Domingos, Kamila L S Rocha, Jessica M Graciano, Lara R Almeida, Jeffrey B Doty, Adriano P Paglia, Danilo B Oliveira, Yoshinori J Nakazawa, Giliane de S Trindade

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Isolation of Orthopoxvirus vaccinia during an outbreak of vesicular disease in dairy cattle from Viçosa, state of Minas Gerais, southeast Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Iago J S DomingosInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-7580-2150
Kamila L S RochaInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Belo Horizonte 31270-901, Brazil.
Jessica M GracianoInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Belo Horizonte 31270-901, Brazil.
Lara R AlmeidaInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Belo Horizonte 31270-901, Brazil.
Jeffrey B DotyU.S. Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, 1600 Clifton Rd. NE, Atlanta, GA 30333, USA.ORCID 0000-0001-5713-9685
Adriano P PagliaInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Belo Horizonte 31270-901, Brazil.
Danilo B OliveiraCentro Integrado de Pesquisa e Pós-Graduação, Universidade Federal dos Vales do Jequitinhonha e Mucuri, MGC 367 Km 583, 5000, Diamantina 39100-000, Brazil.
Yoshinori J NakazawaU.S. Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, 1600 Clifton Rd. NE, Atlanta, GA 30333, USA.
Giliane de S TrindadeInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antonio Carlos, 6627, Belo Horizonte 31270-901, Brazil.ORCID 0000-0003-0785-4298
Universidade Federal de Minas Gerais · BRCenters for Disease Control and Prevention · USUniversidade Federal dos Vales do Jequitinhonha e Mucuri · BR

Funding

CDC HHS 3183DOTMULX
6 · The paper itself

Abstract

Vaccinia virus (VACV) is the causative agent of an emerging viral zoonosis called bovine vaccinia (BV). Several studies have documented characteristics of VACV infections in Brazil; however, the manner in which this virus is maintained in wildlife remains unknown. This work investigated the presence of viral DNA and anti-orthopoxvirus (OPXV) antibodies in samples collected from small mammals in a VACV-endemic area in Minas Gerais, Brazil, in the absence of current outbreaks. Samples did not show amplification of OPXV DNA in molecular tests. However, 5/142 serum samples demonstrated the presence of anti-OPXV neutralizing antibodies in serological tests. These data reinforce the involvement of small mammals in the natural cycle of VACV, highlighting the need for further ecological studies to better understand how this virus is maintained in nature and to develop measures to prevent BV outbreaks.

Indexed as

Communicable DiseasesOrthopoxvirusVacciniaAnimalsBrazilCattleDisease OutbreaksMammalsVaccinia virusZoonosesanimal diseasesecologyepidemiologypublic healthVaccinia virus

Identifiers

PMID37112823
PMCPMC10144947
OpenAlexW4361007397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.