Evidence map›Paper›PMID 37112799›Full record

ArticleViruses2023

Stopping Feline Coronavirus Shedding Prevented Feline Infectious Peritonitis.

Diane D Addie, Flora Bellini, Johanna Covell-Ritchie, Ben Crowe, Sheryl Curran, Mark Fosbery, Stuart Hills, Eric Johnson, Carrie Johnson, Steven Lloyd and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Feline Coronavirus Prevalence in 493 Cats With Chronic Diarrhea.Journal of veterinary internal medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Diane D AddieMaison Zabal, 64470 Etchebar, France.ORCID 0000-0001-7843-2661
Flora BelliniIndependent Researcher, Flora Bellini, Uxbridge, UK.
Johanna Covell-RitchieIndependent Researcher, Johanna Covell-Ritchie, Maidstone, UK.
Ben CroweIndependent Researcher, Ben Crowe, Uxbridge, UK.
Sheryl CurranIndependent Researcher, Sheryl Curran, Baker Street Ragdolls, Liverpool, UK.
Mark FosberyMark Fosbery, Newnham Vets, Maidstone, UK.
Stuart HillsStuart Hills, Ark Veterinary Centre, Lockerbie, UK.
Eric JohnsonIndependent Researcher, Eric Johnson, Firestone, CO, USA.
Carrie JohnsonIndependent Researcher, Carrie Johnson, Firestone, CO, USA.
Steven LloydSteve Lloyd, Zoologix Laboratory, CA, USA.
Oswald JarrettOswald Jarrett, Glasgow, UK.
Maison des Sciences de l'Homme · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After an incubation period of weeks to months, up to 14% of cats infected with feline coronavirus (FCoV) develop feline infectious peritonitis (FIP): a potentially lethal pyogranulomatous perivasculitis. The aim of this study was to find out if stopping FCoV faecal shedding with antivirals prevents FIP. Guardians of cats from which FCoV had been eliminated at least 6 months earlier were contacted to find out the outcome of their cats; 27 households were identified containing 147 cats. Thirteen cats were treated for FIP, 109 cats shed FCoV and 25 did not; a 4-7-day course of oral GS-441524 antiviral stopped faecal FCoV shedding. Follow-up was from 6 months to 3.5 years; 11 of 147 cats died, but none developed FIP. A previous field study of 820 FCoV-exposed cats was used as a retrospective control group; 37 of 820 cats developed FIP. The difference was statistically highly significant (

Indexed as

Coronavirus, FelineCoronavirus InfectionsFeline Infectious PeritonitisAnimalsAntiviral AgentsCatsRetrospective StudiesAntiviral Agentsantiviralchronic enteritisdiarrhoeafeline coronavirusfeline infectious peritonitisFIP preventionGS-441524IBDinflammatory bowel diseaseitraconazole

Identifiers

PMID37112799
PMCPMC10146023
OpenAlexW4360858841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.